… We designed and standardized ICP assays to identify inhibitors of SARS-CoV-2 proteases …
protease inhibitors, we developed this assay to measure the SARS-CoV-2 protease inhibition …

… In this communication, we developed a PBNA for evaluation of anti-viral measures for
SARS-CoV-2, which would be used to evaluate the inhibition of viral attachment and entry …

… Potential inhibitors against SARS-CoV-2 M pro were screened by an enzymatic inhibition
assay. When the different compounds were added into the enzymatic reaction mixture, the …

… A collection of 19 antiviral drugs was tested in the SARS-CoV CPE inhibition assay (Table
2). The set of drugs tested included seven interferons, five nucleoside analogs, three protease …

… inhibitors based on the enzymatic assay … assay greatly facilitates our lead optimization,
and we routinely rely on the FlipGFP assay results to prioritize M pro inhibitors for the SARS-CoV…

… method to probe inhibitory compounds against SARS-CoV-2 … diluted to 2 µM when the
inhibitory assay was carried out. … We applied the library to assay SARS-CoV-2 3CLpro. Using …

… products to inhibit coronavirus and targets … SARS-CoV-2. Due to the similarity in the RNA
genome, main proteases, and primary host receptor between SARS-CoV and SARS-CoV-2, a …

… method to probe SARS-CoV 3CLpro inhibitory compounds. A … was diluted to 1 μM when the
inhibitory assay was going on. … We applied the library to assay SARS-CoV 3CLpro. Using 64 …

… nsp14 increases resistance of SARS-CoV-2 RdRp to nucleotide analog inhibitors. We also
… SARS-CoV-2 RdRp assay which can be deployed to discover SARS-CoV-2 RdRp inhibitors …

… and Ranolazine in this orthogonal assay. As these compounds were selected from an initial
screening assay based on SARS-CoV-2-mediated CPE inhibition, we cannot exclude that …