Formulation and process design for a solid dosage form containing a spray-dried amorphous dispersion of ibipinabant

MM Leane, W Sinclair, F Qian, R Haddadin… - Pharmaceutical …, 2013 - Taylor & Francis
… the solid dispersion may stabilise the amorphous form, … between excipients and the
amorphous dispersion. In addition, … on the way to a coated solid dosage form, are all known risk …

Amorphous solid dispersions

N Shah, H Sandhu, DS Choi, H Chokshi… - Theory and Practice; …, 2014 - Springer
… We believe that many pharmaceutical scientists face … dosage forms for toxicological and
clinical studies as well as for the market. He has a special interest in amorphous solid dispersion

[HTML][HTML] Pharmaceutical amorphous solid dispersion: A review of manufacturing strategies

SV Bhujbal, B Mitra, U Jain, Y Gong, A Agrawal… - … Pharmaceutica Sinica B, 2021 - Elsevier
Amorphous solid dispersions (ASDs) are popular for enhancing the solubility and
bioavailability of poorly water-soluble drugs. Various approaches have been employed to produce …

Barrier coated drug layered particles for enhanced performance of amorphous solid dispersion dosage form

V Puri, AK Dantuluri, AK Bansal - Journal of pharmaceutical sciences, 2012 - Elsevier
… (ASDs) may entail tailor-made dosage form design to exploit … amorphous celecoxib solid
dispersion (ACSD) comprising of … fast dispersing robust high drug load ASD based dosage form. …

Assessing the performance of amorphous solid dispersions

A Newman, G Knipp, G Zografi - Journal of pharmaceutical sciences, 2012 - Elsevier
… Bioavailability in practice refers to the rate and extent of absorption into the blood/plasma
from a dosage form and is related to pharmacokinetics (PK). Bioactivity is due to the API …

Amorphous drugs and dosage forms

H Grohganz, K Löbmann, P Priemel, KT Jensen… - Journal of Drug Delivery …, 2013 - Elsevier
… for enhanced performance of amorphous solid dispersion dosage form J. Pharm. Sci. …
particles for enhanced performance of amorphous solid dispersion dosage form J. Pharm. Sci. …

Characterizing and exploring the differences in dissolution and stability between crystalline solid dispersion and amorphous solid dispersion

X Wang, L Zhang, D Ma, X Tang, Y Zhang, T Yin… - Aaps …, 2020 - Springer
amorphous solid dispersions or crystalline solid dispersions. … Thus, amorphous solid
dispersions are typically prepared as … In this study, an amorphous solid dispersion having a drug …

The influence of crushing amorphous solid dispersion dosage forms on the in-vitro dissolution kinetics

T Pas, S Verbert, B Appeltans… - International Journal of …, 2020 - Elsevier
… existing knowledge gap on the crushability of solid dosage forms of ASDs, major regulatory,
… to investigate the influence of crushing of solid dosage forms of ASDs (tablets and capsules) …

Amorphous solid dispersions: Rational selection of a manufacturing process

T Vasconcelos, S Marques, J das Neves… - Advanced drug delivery …, 2016 - Elsevier
… originates amorphous solid dispersions and uses polymeric carriers. The third generation
comprises amorphous solid dispersion composed by a combination of amorphous carriers …

Selective laser sintering 3-dimensional printing as a single step process to prepare amorphous solid dispersion dosage forms for improved solubility and dissolution …

DA Davis Jr, R Thakkar, Y Su, RO Williams III… - … of pharmaceutical …, 2021 - Elsevier
… This study reports the development of ritonavir-copovidone amorphous solid dispersions (ASDs)
and dosage forms thereof using selective laser sintering (SLS) 3-dimensional (3-D) …