From original antigenic sin to the universal influenza virus vaccine

C Henry, AKE Palm, F Krammer, PC Wilson - Trends in immunology, 2018 - cell.com
… previous exposure to influenza virus shapes antibody responses to vaccination and infection
is … effective development of a universal influenza vaccine. Antibody Responses to Influenza

Is it possible to develop a “universalinfluenza virus vaccine? Outflanking antibody immunodominance on the road to universal influenza vaccination

D Angeletti, JW Yewdell - Cold Spring Harbor …, 2018 - cshperspectives.cshlp.org
… resources to develop influenza vaccines that provide more predictable and durable protection.
Vaccines based on inducing antibodies to the conserved stem of the viral hemagglutinin (…

[HTML][HTML] History and evolution of influenza control through vaccination: from the first monovalent vaccine to universal vaccines

I BARBERIS, P MYLES, SK Ault… - Journal of preventive …, 2016 - ncbi.nlm.nih.gov
… of a universal influenza vaccine that could offer protection against all influenza virus strains,
… of co-circulation of different viral strains. Another important priority is to identify sustainable …

Strategies towards universal pandemic influenza vaccines

F He, S Leyrer, J Kwang - Expert Review of Vaccines, 2016 - Taylor & Francis
… progress in universal influenza vaccine development. … influenza viruses, such as avian
influenza H5N1 and pandemic 2009 H1N1, the development of universal influenza vaccine

Development of universal influenza vaccines targeting conserved viral proteins

SD Jazayeri, CL Poh - Vaccines, 2019 - mdpi.com
influenza virus strains could originate from poultry and swine viruses, development of a new
universal influenza vaccineviruses from different hosts. This review discusses how the new …

Vaccines for influenza

EP Tsilibary, SA Charonis, AP Georgopoulos - Vaccines, 2021 - mdpi.com
… a universal influenza vaccine as one of pivotal importance, given that influenza viruses infect
… In an attempt to reduce influenza disease burden while universal vaccines are developed …

Making universal influenza vaccines: lessons from the 1918 pandemic

DM Morens, JK Taubenberger - The Journal of infectious …, 2019 - academic.oup.com
… of universal influenza vaccines. Challenges to producing a truly universal influenza vaccine
include eliciting broad protection against antigenically different influenza viruses that can …

Universal influenza vaccines, science fiction or soon reality?

RD de Vries, AF Altenburg… - … review of vaccines, 2015 - Taylor & Francis
influenza A viruses. Here, we summarize some of the efforts that are ongoing to develop
universal influenza vaccines… Obviously, an universal influenza vaccine should target more …

Options and obstacles for designing a universal influenza vaccine

YH Jang, BL Seong - Viruses, 2014 - mdpi.com
… This review summarizes recent advancements in the HA stalk-based universal influenza
vaccines, … future guidelines towards the design of a truly protective universal influenza vaccine. …

Advances in the development of influenza virus vaccines

F Krammer, P Palese - Nature reviews Drug discovery, 2015 - nature.com
… or universal influenza virus coverage are … universal influenza virus vaccines could abolish
the need for annual reformulation and re-administration of seasonal influenza virus vaccines