Naphthoquinones: A continuing source for discovery of therapeutic antineoplastic agents

HY Qiu, PF Wang, HY Lin, CY Tang… - Chemical biology & …, 2018 - Wiley Online Library
Naturally occurring naphthoquinones, usually in forms of botanical extracts, have been
implicated with human life since ancient time, far earlier than their isolation and identification …

The diverse mechanisms and anticancer potential of naphthoquinones

CE Pereyra, RF Dantas, SB Ferreira, LP Gomes… - Cancer Cell …, 2019 - Springer
Cancer is one of the leading causes of death around the world and although the different
clinical approaches have helped to increase survival rates, incidence is still high and so its …

Recent development on naphthoquinone derivatives and their therapeutic applications as anticancer agents

VK Tandon, S Kumar - Expert Opinion on Therapeutic Patents, 2013 - Taylor & Francis
Introduction: A large number of natural products including several synthetic drugs possess
naphthoquinone chromophore. Various methods have been devised for their synthesis …

Understanding cancer and the anticancer activities of naphthoquinones–a review

KW Wellington - RSC advances, 2015 - pubs.rsc.org
The non-communicable disease, cancer, is one of the major causes of death across the
world and is forecast to increase by 75% to reach close to 25 million cases over the next two …

Naphthoquinones and derivatives as potential anticancer agents: An updated review

MM Rahman, MR Islam, S Akash, S Shohag… - Chemico-Biological …, 2022 - Elsevier
One of the leading global causes of death is cancer; even though several treatment methods
have improved survival rates, the incidence and fatality rates remain high. Naphthoquinones …

Noteworthy secondary metabolites naphthoquinones-their occurrence, pharmacological properties and analysis

P Babula, V Adam, L Havel… - Current Pharmaceutical …, 2009 - ingentaconnect.com
Chemical investigation of many bacterial and fungal, as well as plant species has revealed
the presence of interesting compounds derived from naphthalene-1, 4-naphthoquinones …

The relevance and insights on 1, 4-naphthoquinones as antimicrobial and antitumoral molecules: A systematic review

G Navarro-Tovar, S Vega-Rodríguez, E Leyva… - Pharmaceuticals, 2023 - mdpi.com
Natural product derivatives are essential in searching for compounds with important
chemical, biological, and medical applications. Naphthoquinones are secondary …

First synthesis and anticancer activity of novel naphthoquinone amides

N Pradidphol, N Kongkathip, P Sittikul… - European journal of …, 2012 - Elsevier
Sixteen novel naphthoquinone aromatic amides were synthesized by a new route starting
from 1-hydroxy-2-naphthoic acid in nine or ten steps with good to excellent yield. Amide …

Naphthoquinone derivatives isolated from plants: recent advances in biological activity

ES Ahmadi, A Tajbakhsh, M Iranshahy… - Mini Reviews in …, 2020 - ingentaconnect.com
Naturally occurring naphthoquinones (NQs) comprising highly reactive small molecules are
the subject of increasing attention due to their promising biological activities such as …

Bioactive naphthoquinones from higher plants

I Hook, C Mills, H Sheridan - Studies in natural products chemistry, 2014 - Elsevier
This review analyzes the more recent publications concerning the distribution, chemistry,
and bioactivities of naphthoquinones (NQs) in higher plants. These highly reactive …