Design, synthesis, biological evaluation, and antioxidant and cytotoxic activity of heteroatom-substituted 1, 4-naphtho-and benzoquinones

NG Deniz, C Ibis, Z Gokmen, M Stasevych… - Chemical and …, 2015 - jstage.jst.go.jp
Design, Synthesis, Biological Evaluation, and Antioxidant and Cytotoxic Activity of
Heteroatom-Substituted 1,4-Naphtho- and Benzoquinones Toggle navigation J-STAGE home …

[PDF][PDF] Synthesis, antioxidant and cytotoxic activities of novel naphthoquinone derivatives from 2, 3-dihydro-2, 3-epoxy-1, 4-naphthoquinone

MA Berghot, EM Kandeel, AH Abdel-Rahman… - Med. Chem, 2014 - researchgate.net
A series of newly naphthoquinone derivatives were synthesized using 2, 3-dihydro-2, 3-
epoxy-1, 4-naphthoquinone (1) as a starting material. The corresponding acetophenyl …

Synthesis, characterization and antiproliferative activity of 1, 2-naphthoquinone and its derivatives

S Shukla, RS Srivastava, SK Shrivastava… - Applied biochemistry …, 2012 - Springer
In the present study substituted 1, 2-naphthoquinones were synthesized, purified and
characterized by spectroscopic studies (UV, FT-IR, 1 H NMR, 13 C NMR and elemental …

Antioxidant, antiproliferative, and acetylcholinesterase inhibition activity of amino alcohol derivatives from 1, 4-naphthoquinone

A Estolano-Cobián, E Noriega-Iribe… - Medicinal Chemistry …, 2020 - Springer
Natural and synthetic naphthoquinones have demonstrated numerous biological activities;
therefore, they provide an interesting scaffold for medicinal chemists in the search for new …

Synthesis and cytotoxic evaluation of a series of 2-amino-naphthoquinones against human cancer cells

TAP De Moraes, MJS Filha, CA Camara, TMS Silva… - Molecules, 2014 - mdpi.com
The cytotoxicity of a series of aminonaphthoquinones resulting from the reaction of suitable
aminoacids with 1, 4-naphthoquinone was assayed against SF-295 (glioblastoma), MDAMB …

Elucidation of structure–activity relationships for 2-or 6-substituted-5, 8-dimethoxy-1, 4-naphthoquinones

RP Verma, C Hansch - Bioorganic & medicinal chemistry, 2004 - Elsevier
1, 4-Naphthoquinones have already been recognized to possess a wide range of biological
activities. We have developed quantitative structure activity relationships (QSAR) for different …

Synthesis and evaluation of novel 1, 4-naphthoquinone derivatives as antiviral, antifungal and anticancer agents

VK Tandon, RV Singh, DB Yadav - Bioorganic & medicinal chemistry letters, 2004 - Elsevier
The synthesis and evaluation of some 2-substituted-1, 4-naphthoquinones 2, S-(1, 4-
naphthoquinon-2-yl)-mercaptoalkanoic acid amides 4, related benzoquinone and …

Nucleophilic substitution reactions of 1,4-naphthoquinone and biologic properties of novel S-, S,S-, N-, and N,S-substituted 1,4-naphthoquinone derivatives

C Ibis, AF Tuyun, H Bahar, SS Ayla… - Medicinal Chemistry …, 2014 - Springer
A novel series of S-, S, S-, N-and N, S-substituted 1, 4-naphthoquinone derivatives were
synthesized and evaluated for their antibacterial and antifungal activity. Among the …

Synthesis and antiproliferative evaluation of some 1, 4-naphthoquinone derivatives against human cervical cancer cells

A Kacmaz, NG Deniz, SG Aydinli, C Sayil… - Open …, 2019 - degruyter.com
In the course of biological properties of quinone derivatives, the N (H)-, S-and S, S-
substituted-1, 4-naphthoquinones were synthesized by reactions of 2, 3-dichloro-1, 4 …

6-substituted 1, 4-naphthoquinone oxime derivatives (I): synthesis and evaluation of their cytotoxic activity

G Huang, H Zhao, W Zhou, J Dong, Q Zhang… - Monatshefte für Chemie …, 2017 - Springer
Abstract A series of 6-substituted 1, 4-naphthoquinone oxime derivatives were synthesized
and evaluated for their in vitro cytotoxicity against four cancer cell lines and one normal cell …