Anti-inflammatory and anti-arthritic activities of 3, 4-dihydro-2, 2-dimethyl-2H-naphthol [1, 2-b] pyran-5, 6-dione (β-lapachone)

MM Sitônio, CHR de Carvalho Júnior, IA Campos… - Inflammation …, 2013 - Springer
Objective and design The purpose of this study was to evaluate the anti-inflammatory and
anti-arthritic activities of 3, 4-dihydro-2, 2-dimethyl-2H-naphthol [1, 2-b] pyran-5, 6-dione (β …

An evaluation on potential anti-inflammatory effects of β-lapachone

N Mokarizadeh, P Karimi, H Kazemzadeh… - International …, 2020 - Elsevier
Inflammation plays a significant role in the pathogenesis of chronic diseases. Inflammatory
diseases such as bacterial diseases, Alzheimer's disease, rheumatoid arthritis, multiple …

Synthesis and anti-inflammatory evaluations of β-lapachone derivatives

CH Tseng, CM Cheng, CC Tzeng, SI Peng… - Bioorganic & medicinal …, 2013 - Elsevier
β-Lapachone (β-LAPA), a natural product from the lapacho tree in South America, is a
potential chemotherapeutic agent that exhibit a wide variety of pharmacological effects such …

β-Lapachone suppresses neuroinflammation by modulating the expression of cytokines and matrix metalloproteinases in activated microglia

EJ Lee, HM Ko, YH Jeong, EM Park, HS Kim - Journal of …, 2015 - Springer
Background β-Lapachone (β-LAP) is a natural naphthoquinone compound isolated from the
lapacho tree (Tabebuia sp.), and it has been used for treatment of rheumatoid arthritis …

Diarylheptanoid, a constituent isolated from methanol extract of Alpinia officinarum attenuates TNF-α level in Freund's complete adjuvant-induced arthritis in rats

VS Honmore, AD Kandhare, PP Kadam… - Journal of …, 2019 - Elsevier
Ethnopharmacological relevance Rheumatoid arthritis (RA) is a chronic inflammatory and
destructive joint disease that affects the worldwide population. Alpinia officinarum Hance …

Anti-inflammatory effect of YPE-01, a novel diarylheptanoid derivative, on dermal inflammation in mice

R Yamazaki, R Aiyama, T Matsuzaki, S Hashimoto… - Inflammation …, 1998 - Springer
Abstract Objective and Design: We investigated the anti-inflammatory effect of YPE-01, a
novel diarylheptanoid derivative in vitro and in vivo.¶ Material: In the in vitro study, rat …

Anti-inflammatory and analgesic effect of plumbagin through inhibition of nuclear factor-κB activation

P Luo, YF Wong, L Ge, ZF Zhang, Y Liu, L Liu… - Journal of Pharmacology …, 2010 - ASPET
Plumbagin (5-hydroxy-2-methyl-1, 4-naphthoquinone)(PL) is a naturally occurring yellow
pigment found in the plants of the Plumbaginaceae, Droseraceae, Ancistrocladaceae, and …

Anti-inflammatory effects of β-lapachone in lipopolysaccharide-stimulated BV2 microglia

DO Moon, YH Choi, ND Kim, YM Park… - International …, 2007 - Elsevier
β-Lapachone (LAPA) is a chemotherapeutic agent that can inhibit the expression of nitric
oxide (NO) and inducible NO synthase (iNOS) in alveolar macrophages. No other …

Anti-inflammatory Activity of n-Propyl Gallate Through Down-regulation of NF-κB and JNK Pathways

HJ Jung, SJ Kim, WK Jeon, BC Kim, K Ahn, K Kim… - Inflammation, 2011 - Springer
The present study aimed to assess anti-inflammatory activity and underlying mechanism of n-
propyl gallate, the n-propyl ester of gallic acid. n-Propyl gallate was shown to contain anti …

Anti-inflammatory effect of (E)-4-(3, 7-dimethylocta-2, 6-dienylamino) phenol, a new derivative of 4-nerolidylcatechol

RC Lino, FI Martins, IF Florentino… - Journal of Pharmacy …, 2013 - academic.oup.com
Objectives We have investigated the anti-inflammatory and antinociceptive effects of (E)-4-
(3, 7-dimethylocta-2, 6-dienylamino) phenol (LQFM-015), which was designed through …