Biological targets of isothiocyanates
KK Brown, MB Hampton - Biochimica et Biophysica Acta (BBA)-General …, 2011 - Elsevier
BACKGROUND: Isothiocyanates are phytochemicals with a broad array of effects in
biological systems. Bioactivity includes the stimulation of cellular antioxidant systems …
biological systems. Bioactivity includes the stimulation of cellular antioxidant systems …
Natural isothiocyanates: genotoxic potential versus chemoprevention
C Fimognari, E Turrini, L Ferruzzi, M Lenzi… - … Research/Reviews in …, 2012 - Elsevier
Isothiocyanates, occurring in many dietary cruciferous vegetables, show interesting
chemopreventive activities against several chronic–degenerative diseases, including …
chemopreventive activities against several chronic–degenerative diseases, including …
Cancer-preventive isothiocyanates: dichotomous modulators of oxidative stress
Isothiocyanates (ITCs), a class of phytochemicals with promising cancer-preventive
potential, are double-edged swords in the modulation of cellular oxidative stress. While ITCs …
potential, are double-edged swords in the modulation of cellular oxidative stress. While ITCs …
[HTML][HTML] Are isothiocyanates potential anti-cancer drugs?
X Wu, Q Zhou, K Xu - Acta Pharmacologica Sinica, 2009 - nature.com
Isothiocyanates are naturally occurring small molecules that are formed from glucosinolate
precursors of cruciferous vegetables. Many isothiocyanates, both natural and synthetic …
precursors of cruciferous vegetables. Many isothiocyanates, both natural and synthetic …
Proteins as binding targets of isothiocyanates in cancer prevention
L Mi, AJ Di Pasqua, FL Chung - Carcinogenesis, 2011 - academic.oup.com
Isothiocyanates are versatile cancer-preventive compounds. Evidence from animal studies
indicates that the anticarcinogenic activities of ITCs involve all the major stages of tumor …
indicates that the anticarcinogenic activities of ITCs involve all the major stages of tumor …
Naturally occurring isothiocyanates exert anticancer effects by inhibiting deubiquitinating enzymes
The anticancer properties of cruciferous vegetables are well known and attributed to an
abundance of isothiocyanates such as benzyl isothiocyanate (BITC) and phenethyl …
abundance of isothiocyanates such as benzyl isothiocyanate (BITC) and phenethyl …
[HTML][HTML] Dietary isothiocyanates: Novel insights into the potential for cancer prevention and therapy
G Na, C He, S Zhang, S Tian, Y Bao… - International Journal of …, 2023 - mdpi.com
Diet plays an important role in health. A high intake of plant chemicals such as
glucosinolates/isothiocyanates can promote optimal health and decrease the risk of cancer …
glucosinolates/isothiocyanates can promote optimal health and decrease the risk of cancer …
Isothiocyanates: a class of bioactive metabolites with chemopreventive potential
In recent years, growing interest has been focused on the field of chemoprevention using
natural therapies. The reason to turn toward “natural” remedies is associated with diverse …
natural therapies. The reason to turn toward “natural” remedies is associated with diverse …
Identification of potential protein targets of isothiocyanates by proteomics
L Mi, BL Hood, NA Stewart, Z Xiao… - Chemical research in …, 2011 - ACS Publications
Isothiocyanates (ITCs), such as phenethyl isothiocyanate (PEITC) and sulforaphane (SFN),
are effective cancer chemopreventive compounds. It is believed that the major mechanism …
are effective cancer chemopreventive compounds. It is believed that the major mechanism …
Isothiocyanates as novel cytotoxic and cytostatic agents: molecular pathway on human transformed and non-transformed cells
C Fimognari, M Nüsse, F Berti, R Iori… - Biochemical …, 2004 - Elsevier
Cancer chemoprevention is a new approach in the management of cancer. Traditional
cytotoxic chemotherapeutic approaches cannot cure most advanced solid malignancies …
cytotoxic chemotherapeutic approaches cannot cure most advanced solid malignancies …