Plumbagin (5-hydroxy-2-methyl-1, 4-naphthoquinone)(PL) is a naturally occurring yellow
pigment found in the plants of the Plumbaginaceae, Droseraceae, Ancistrocladaceae, and …

Plumbagin (PL) has been reported to exhibit anti-carcinogenic, anti-inflammatory and
analgesic activities, but little is known about its mechanism. In this study, we investigated the …

Phytochemicals from various medicinal plants are well known for their antioxidant properties
and anti-cancer effects. Many of these bioactive compounds or natural products have …

The roots of Angelica tenuissima have been commonly used for the treatment of
cardiovascular diseases and menstrual discomfort in Asian countries, such as China and …

The present study was aimed to investigate the effects of guggulsterone (GS) on
proinflammatory responses as well as the underlying molecular mechanisms in macrophage …

Plumbagin (5-hydroxy-2-methyl-1, 4-naphthoquinone), a quinone isolated from the roots of
Plumbago zeylanica was recently reported to suppress the activation of NF-κB in tumor cells …

Abstract Punicalagin (2, 3, hexahydroxydiphenoyl-gallagyl-d-glucose and referred to as
PUN) is a bioactive ellagitannin isolated from pomegranate, which is widely used for the …

Nuclear factor-κB (NF-κB) and the signaling pathways that regulate its activity have become
a focal point for intense drug discovery and development efforts. NF-κB regulates the …

The aims of this study were to evaluate the anti‐inflammatory and analgesic effects of
bufalin, a major component of “Chan‐su.” We used a carrageenan‐induced paw edema …

This study aimed to explore the effects of plumbagin on rheumatoid arthritis (RA) and its
mechanism. The RA cell model was simulated following the treatment of interleukin-1β (IL …