The pursuit of effective anticancer therapies has led to a burgeoning interest in the realm of
redox modulation. This review provides a comprehensive exploration of the intricate …

Redox dysregulation originating from metabolic alterations and dependence on mitogenic
and survival signaling through reactive oxygen species represents a specific vulnerability of …

Significance: Cancer is related to redox biology from many points of view, such as initiation
and promotion, metabolism and growth, invasion and metastasis, vascularization, or through …

Significance: There are a number of redox-active anticancer agents currently in
development based on the premise that altered redox homeostasis is necessary for cancer …

Background: Resistance to standard therapeutic methods, including chemotherapy,
immunotherapy, and targeted therapy, remains a critical challenge in effective cancer …

Chemotherapy continues to be the main treatment option for cancer. Although systemic
chemotherapy can efficiently eradicate cancer cells, a significant proportion of patients carry …

Cancer remains the second leading cause of death worldwide. Research is currently
focused on finding novel anticancer therapies and elucidating their mechanisms of action …

Apoptosis is an essential and highly conserved process for the maintenance of tissue
homeostasis and involves a programmed series of events for the removal of effete …

Antioxidants play a pivotal role in neutralizing reactive oxygen species (ROS), which are
known to induce oxidative stress. In the context of cancer development, cancer cells adeptly …

Intracellular reduction–oxidation (redox) homeostasis, mediated mainly by reactive oxygen
species (ROS), plays a significant role in physiological function maintenance and regulation …