Tumours exhibit higher basal levels of reactive oxygen species (ROS) and altered redox
environment compared to normal cells. Excessive level of ROS can be toxic to these cells …

Cancer cells are particularly vulnerable to treatments impairing redox homeostasis. Reactive
oxygen species (ROS) can indeed play an important role in the initiation and progression of …

Cancer cell resistance to chemotherapy is still a heavy burden that impairs the response of
many cancer patients to conventional chemotherapy. Using drug combinations is one …

Nature is an inexhaustible reservoir of compounds with healing properties, and people used
natural products to treat different medical conditions from ancient times. One of the main …

The modulation of oxidative stress is essential for the maintenance of redox homeostasis in
healthy and cancer cells. In fact, although cancer cells are characterized by the …

Oxidative stress is often considered as a causative factor in carcinogenesis. In addition,
current knowledge recognizes oxidative stress as a mechanism by which various cancer …

The vulnerability of some cancer cells to oxidative signals is a therapeutic target for the
rational design of new anticancer agents. In addition to their well characterized effects on …

Redox dysregulation originating from metabolic alterations and dependence on mitogenic
and survival signaling through reactive oxygen species represents a specific vulnerability of …

Significance: Cancer is related to redox biology from many points of view, such as initiation
and promotion, metabolism and growth, invasion and metastasis, vascularization, or through …

The pursuit of effective anticancer therapies has led to a burgeoning interest in the realm of
redox modulation. This review provides a comprehensive exploration of the intricate …