Noteworthy secondary metabolites naphthoquinones-their occurrence, pharmacological properties and analysis

P Babula, V Adam, L Havel… - Current Pharmaceutical …, 2009 - ingentaconnect.com
Chemical investigation of many bacterial and fungal, as well as plant species has revealed
the presence of interesting compounds derived from naphthalene-1, 4-naphthoquinones …

Naphthoquinones: A continuing source for discovery of therapeutic antineoplastic agents

HY Qiu, PF Wang, HY Lin, CY Tang… - Chemical biology & …, 2018 - Wiley Online Library
Naturally occurring naphthoquinones, usually in forms of botanical extracts, have been
implicated with human life since ancient time, far earlier than their isolation and identification …

Synthesis and antimicrobial evaluation of 1, 4‐naphthoquinone derivatives as potential antibacterial agents

P Ravichandiran, M Masłyk, S Sheet… - …, 2019 - Wiley Online Library
Naphthoquinones are an important class of compounds present in a number of natural
products. In this study, a new series of 1, 4‐naphthoquinone derivatives were synthesized …

Naphthoquinones and their pharmacological properties

P Babula, V Adam, L Havel, R Kizek - Ceska a Slovenska farmacie …, 2007 - europepmc.org
Naphthoquinones are wide-spread phenolic compounds in nature. They are products of
bacterial and fungal as well as high-plants secondary metabolism. Juglone, lawsone, and …

Synthesis, antibacterial and antifungal activities of naphthoquinone derivatives: a structure–activity relationship study

JM Sánchez-Calvo, GR Barbero… - Medicinal Chemistry …, 2016 - Springer
Abstract The synthesis of 1, 4-naphthoquinone derivatives is of great interest since these
compounds exhibit strong activity as antimalarial, antibacterial, antifungal and anticancer …

[HTML][HTML] Naphthoquinones: biological properties and synthesis of lawsone and derivatives-a structured review

LI López López, SD Nery Flores, SY Silva Belmares… - Vitae, 2014 - scielo.org.co
Background: Naphthoquinones are natural pigments that are widely distributed in nature
and have important biological activities. Lawsone (2-hydroxy-1, 4-naphthoquinone) and its …

Synthesis and evaluation of bioactive naphthoquinones from the Brazilian medicinal plant, Tabebuia avellanedae

M Yamashita, M Kaneko, H Tokuda, K Nishimura… - Bioorganic & medicinal …, 2009 - Elsevier
A series of naphthoquinones based on the naphtho [2, 3-b] furan-4, 9-dione skeleton such
as (−)-5-hydroxy-2-(1′-hydoxyethyl) naphtho [2, 3-b] furan-4, 9-dione (1) and its positional …

1, 4-Naphthoquinones: some biological properties and application

D Aminin, S Polonik - Chemical and Pharmaceutical Bulletin, 2020 - jstage.jst.go.jp
Over the past decade, a number of new 1, 4-naphthoquinones have been isolated from
natural sources and new 1, 4-naphthoquinones with diverse structural features have been …

Naphthylisoquinoline alkaloids potential drug leads

SRM Ibrahim, GA Mohamed - Fitoterapia, 2015 - Elsevier
Naphthylisoquinolines are a group of structurally diverse secondary metabolites, consisting
of naphthalene and isoquinoline moieties. Naturally occurring naphthylisoquinolines have …

Antifungal and antibacterial naphthoquinones from Newbouldia laevis roots

S Gafner, JL Wolfender, M Nianga, H Stoeckli-Evans… - Phytochemistry, 1996 - Elsevier
From a dichloromethane extract of Newbouldia laevis roots, four new (6-hydroxydehydroiso-
α-lapachone, 7-hydroxydehydroiso-α-lapachone, 5, 7-dihydroxydehydroiso-α-lapachone …