Lawsone in organic synthesis

AK Jordão, MD Vargas, AC Pinto, FC da Silva… - RSC …, 2015 - pubs.rsc.org
Lawsone (1) is a special naphthoquinone that is useful for many applications in various
scientific and technological fields. For over 100 years, it has been used as the starting …

[HTML][HTML] Naphthoquinones: biological properties and synthesis of lawsone and derivatives-a structured review

LI López López, SD Nery Flores, SY Silva Belmares… - Vitae, 2014 - scielo.org.co
Background: Naphthoquinones are natural pigments that are widely distributed in nature
and have important biological activities. Lawsone (2-hydroxy-1, 4-naphthoquinone) and its …

Reaction between lawsone and aminophenol derivatives: Synthesis, characterization, molecular structures and antiproliferative activity

L Kathawate, PV Joshi, TK Dash, S Pal… - Journal of Molecular …, 2014 - Elsevier
Reaction between two bioreductive reactants lawsone (2-hydroxy-1, 4-napthoquinone) and
derivatives 2-aminophenol without catalyst is reported. The reaction between lawsone and 4 …

A short synthesis of lennoxamine via ynamides

S Couty, C Meyer, J Cossy - Tetrahedron letters, 2006 - Elsevier
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Natural naphthoquinones with great importance in medicinal chemistry

F de Carvalho da Silva… - Current Organic …, 2016 - ingentaconnect.com
This review involves the chemistry and biochemistry of lapachol, β-lapachone and lawsone,
examples of bioactive natural products that still being under biological evaluation and …

Synthesis of dihydrodehydrodiconiferyl alcohol: the revised structure of lawsonicin

J Meng, T Jiang, HA Bhatti, BS Siddiqui… - Organic & …, 2010 - pubs.rsc.org
Structural revision of lawsonicin, a natural product of Lawsonia alba, is reported based upon
comparison of its spectral data with that of the naturally occurring dihydrobenzo [b] furan …

A focused review of synthetic applications of Lawesson's reagent in organic synthesis

H Khatoon, E Abdulmalek - Molecules, 2021 - mdpi.com
Lawesson's reagent (LR) is a well-known classic example of a compound with unique
construction and unusual chemical behavior, with a wide range of applications in synthetic …

Synthesis of pharmacologically important naphthoquinones and anticancer activity of 2-benzyllawsone through DNA topoisomerase-II inhibition

BS Kumar, K Ravi, AK Verma, K Fatima… - Bioorganic & Medicinal …, 2017 - Elsevier
Naphthoquinones are naturally occurring biologically active entities. Practical de novo
syntheses of three naphthoquinones ie lawsone (1), lapachol (2), and β-lapachone (3b) …

Recent advances in the synthesis of diarylheptanoids

K Sudarshan, S Yarlagadda… - Chemistry–An Asian …, 2024 - Wiley Online Library
In the quest for synthesizing biologically important natural products, medicinal chemists
embark on an endless journey. This review focuses on the reports published towards the …

Synthesis, characterization, and antileukemic properties of naphthoquinone derivatives of lawsone

R Inagaki, M Ninomiya, K Tanaka… - ChemMedChem, 2015 - Wiley Online Library
Naphthoquinones are considered privileged structures for anticancer drug molecules. The
Heck reaction of 2‐hydroxy‐1, 4‐naphthoquinone (lawsone) with 1‐bromo‐3‐methyl‐2 …