[HTML][HTML] Current status of 1, 4-Naphthoquinones and their derivatives for wound healing

P Kumari, V Singh, V Kant, M Ahuja - European Journal of Medicinal …, 2024 - Elsevier
Cutaneous wounds are a major healthcare concern affecting millions of people as they fail
to heal properly and can result in life threatening conditions and high economic loss. Wound …

The relevance and insights on 1, 4-naphthoquinones as antimicrobial and antitumoral molecules: A systematic review

G Navarro-Tovar, S Vega-Rodríguez, E Leyva… - Pharmaceuticals, 2023 - mdpi.com
Natural product derivatives are essential in searching for compounds with important
chemical, biological, and medical applications. Naphthoquinones are secondary …

How Thymoquinone from Nigella sativa Accelerates Wound Healing through Multiple Mechanisms and Targets

A Kmail, O Said, B Saad - Current Issues in Molecular Biology, 2023 - mdpi.com
Wound healing is a multifaceted process necessitating the collaboration of numerous
elements to mend damaged tissue. Plant and animal-derived natural compounds have been …

Naphthoquinones: A continuing source for discovery of therapeutic antineoplastic agents

HY Qiu, PF Wang, HY Lin, CY Tang… - Chemical biology & …, 2018 - Wiley Online Library
Naturally occurring naphthoquinones, usually in forms of botanical extracts, have been
implicated with human life since ancient time, far earlier than their isolation and identification …

Exploiting the Anticancer, Antimicrobial and Antiviral Potential of Naphthoquinone Derivatives: Recent Advances and Future Prospects

S Xiang, Y Li, SN Khan, W Zhang, J Cui - 2024 - preprints.org
Cancer remains a primary cause of mortality, with over 18.1 million new cases and 9.6
million deaths globally in 2018. Chemotherapy, which utilizes a spectrum of cytotoxic drugs …

Synthesis of newly functionalized 1, 4-naphthoquinone derivatives and their effects on wound healing in alloxan-induced diabetic mice

SH Cardoso, CR de Oliveira, AS Guimarães… - Chemico-Biological …, 2018 - Elsevier
Naphthoquinone derivatives have various pharmacological properties. Here, we describe
the synthesis of new 1, 4-naphthoquinone derivatives inspired by lawsone and β-lapachone …

Anticancer naphthoquinone derivatives: an updated patent review (2012–19)

FC Demidoff, MN Rennó, CD Netto - Studies in Natural Products Chemistry, 2022 - Elsevier
This chapter provides an overview of anticancer naphthoquinone derivatives patented
between 2012 and 2019, encompassing the synthesis or isolation, pharmacological …

[HTML][HTML] A review on the synthesis and application of naphthoquinone-based drugs

J Khan, A Rani, M Aslam, G Pandey, BN Pant - Results in Chemistry, 2023 - Elsevier
Naphthoquinones are secondary plant metabolites that are used to treat a variety of human
ailments in traditional medicine. In light of this, the synthesis of derivatives of …

1, 4-Naphthoquinone analogues: Potent antibacterial agents and mode of action evaluation

P Ravichandiran, S Sheet, D Premnath, AR Kim… - Molecules, 2019 - mdpi.com
1, 4-Naphthoquinones have antibacterial activity and are a promising new class of
compound that can be used to treat bacterial infections. The goal was to improve effective …

Synthesis and antimicrobial evaluation of 1, 4‐naphthoquinone derivatives as potential antibacterial agents

P Ravichandiran, M Masłyk, S Sheet… - …, 2019 - Wiley Online Library
Naphthoquinones are an important class of compounds present in a number of natural
products. In this study, a new series of 1, 4‐naphthoquinone derivatives were synthesized …