Naphthoquinones and derivatives as potential anticancer agents: An updated review
One of the leading global causes of death is cancer; even though several treatment methods
have improved survival rates, the incidence and fatality rates remain high. Naphthoquinones …
have improved survival rates, the incidence and fatality rates remain high. Naphthoquinones …
Naphthoquinones: A continuing source for discovery of therapeutic antineoplastic agents
HY Qiu, PF Wang, HY Lin, CY Tang… - Chemical biology & …, 2018 - Wiley Online Library
Naturally occurring naphthoquinones, usually in forms of botanical extracts, have been
implicated with human life since ancient time, far earlier than their isolation and identification …
implicated with human life since ancient time, far earlier than their isolation and identification …
Understanding cancer and the anticancer activities of naphthoquinones–a review
KW Wellington - RSC advances, 2015 - pubs.rsc.org
The non-communicable disease, cancer, is one of the major causes of death across the
world and is forecast to increase by 75% to reach close to 25 million cases over the next two …
world and is forecast to increase by 75% to reach close to 25 million cases over the next two …
The diverse mechanisms and anticancer potential of naphthoquinones
CE Pereyra, RF Dantas, SB Ferreira, LP Gomes… - Cancer Cell …, 2019 - Springer
Cancer is one of the leading causes of death around the world and although the different
clinical approaches have helped to increase survival rates, incidence is still high and so its …
clinical approaches have helped to increase survival rates, incidence is still high and so its …
Recent development on naphthoquinone derivatives and their therapeutic applications as anticancer agents
VK Tandon, S Kumar - Expert Opinion on Therapeutic Patents, 2013 - Taylor & Francis
Introduction: A large number of natural products including several synthetic drugs possess
naphthoquinone chromophore. Various methods have been devised for their synthesis …
naphthoquinone chromophore. Various methods have been devised for their synthesis …
The relevance and insights on 1, 4-naphthoquinones as antimicrobial and antitumoral molecules: A systematic review
G Navarro-Tovar, S Vega-Rodríguez, E Leyva… - Pharmaceuticals, 2023 - mdpi.com
Natural product derivatives are essential in searching for compounds with important
chemical, biological, and medical applications. Naphthoquinones are secondary …
chemical, biological, and medical applications. Naphthoquinones are secondary …
Synthesis and evaluation of antitumor activity of novel 1, 4-naphthoquinone derivatives (IV)
BH Kim, J Yoo, SH Park, JK Jung, H Cho… - Archives of pharmacal …, 2006 - Springer
Naphthoquinones are widely distributed in nature and many clinically important antitumor
drugs containing a quinone moiety, such as anthracyclines, mitoxantrones and saintopin …
drugs containing a quinone moiety, such as anthracyclines, mitoxantrones and saintopin …
[HTML][HTML] Cytotoxicity, hemolysis and in vivo acute toxicity of 2-hydroxy-3-anilino-1, 4-naphthoquinone derivatives
VS de Sena Pereira, CBS de Oliveira, F Fumagalli… - Toxicology Reports, 2016 - Elsevier
Abstract The 1, 4-naphthoquinones, important members of the family of quinones are used
as both crude extracts and as compound manipulated by the pharmaceutical industry. They …
as both crude extracts and as compound manipulated by the pharmaceutical industry. They …
Synthesis and anticancer evaluation of 1, 4‐naphthoquinone derivatives containing a phenylaminosulfanyl moiety
P Ravichandiran, SA Subramaniyan, SY Kim… - …, 2019 - Wiley Online Library
Naphthoquinones are exceptional building blocks in organic synthesis and have been used
to synthesize several well‐known pharmaceutically active agents. Herein we report the …
to synthesize several well‐known pharmaceutically active agents. Herein we report the …
[HTML][HTML] Synthesis and biological evaluation of lipophilic 1, 4-naphthoquinone derivatives against human cancer cell lines
SH Wang, CY Lo, ZH Gwo, HJ Lin, LG Chen, CD Kuo… - Molecules, 2015 - mdpi.com
To examine the effect of hydrophobicity on the anticancer activity of 1, 4-naphthoquinone
derivatives, a series of compounds bearing a 2-O-alkyl-, 3-C-alkyl-or 2/3-N-morpholinoalkyl …
derivatives, a series of compounds bearing a 2-O-alkyl-, 3-C-alkyl-or 2/3-N-morpholinoalkyl …