Quinones represent a class of toxicological intermediates, which can create a variety of
hazardous effects in vivo including, acute cytotoxicity, immunotoxicity, and carcinogenesis …

Quinones represent a class of toxicological intermediates which can create a variety of
hazardous effects in vivo, including acute cytotoxicity, immunotoxicity, and carcinogenesis …

Quinones are ubiquitous in nature and constitute an important class of naturally occurring
compounds that are found in plants, fungi, and bacteria and that function primarily as …

Quinones and quinone imines are highly reactive metabolites (RMs) able to induce
dangerous effects in vivo. They are responsible for all kinds of toxicity, for example …

Quinones are widespread in our environment, occurring both naturally and as pollutants.
Human exposure to them is therefore extensive. Quinones also form an important class of …

Quinones are ubiquitous in nature and constitute an important class of naturally occurring
compounds found in plants, fungi and bacteria. Human exposure to quinones therefore …

Quinones are believed to induce their toxicity by two main mechanisms: oxygen activation
by redox cycling and alkylation of essential macromolecules. The physicochemical …

Quinones are probably found in all respiring animal and plant cells. They are widely used as
anticancer, antibacterial or antimalarial drugs and as fungicides. Toxicity can arise as a …

Quinones permeate our biotic environment, contributing to both homeostasis and
cytotoxicity. All quinones generate reactive oxygen species through redox cycling, while …

The overall biological activity of quinones is a function of the physico-chemical properties of
these compounds, which manifest themselves in a critical bimolecular reaction with …