[HTML][HTML] Synthesis, characterization and in-vitro evaluation of novel naphthoquinone derivatives and related imines: Identification of new anticancer leads
Abstract Quinones such as 1, 4-naphthoquinones are abundant in nature and
naphthoquinone based natural products are known to possess anticancer activity. This …
naphthoquinone based natural products are known to possess anticancer activity. This …
Synthesis and biological evaluation of new naphthoquinones derivatives
EM Ourhzif, C Decombat… - Current Organic …, 2020 - ingentaconnect.com
New substituted 1, 4-naphthoquinones have been prepared in good overall yields through
the naphthol route. The cytotoxicity of these compounds was tested in vitro on MCF-7 breast …
the naphthol route. The cytotoxicity of these compounds was tested in vitro on MCF-7 breast …
Recent development on naphthoquinone derivatives and their therapeutic applications as anticancer agents
VK Tandon, S Kumar - Expert Opinion on Therapeutic Patents, 2013 - Taylor & Francis
Introduction: A large number of natural products including several synthetic drugs possess
naphthoquinone chromophore. Various methods have been devised for their synthesis …
naphthoquinone chromophore. Various methods have been devised for their synthesis …
First synthesis and anticancer activity of novel naphthoquinone amides
N Pradidphol, N Kongkathip, P Sittikul… - European journal of …, 2012 - Elsevier
Sixteen novel naphthoquinone aromatic amides were synthesized by a new route starting
from 1-hydroxy-2-naphthoic acid in nine or ten steps with good to excellent yield. Amide …
from 1-hydroxy-2-naphthoic acid in nine or ten steps with good to excellent yield. Amide …
Synthesis, characterization and antiproliferative activity of 1, 2-naphthoquinone and its derivatives
S Shukla, RS Srivastava, SK Shrivastava… - Applied biochemistry …, 2012 - Springer
In the present study substituted 1, 2-naphthoquinones were synthesized, purified and
characterized by spectroscopic studies (UV, FT-IR, 1 H NMR, 13 C NMR and elemental …
characterized by spectroscopic studies (UV, FT-IR, 1 H NMR, 13 C NMR and elemental …
In Vitro and In Vivo Biological Evaluation of Novel 1,4‐Naphthoquinone Derivatives as Potential Anticancer Agents
P Ravichandiran, A Martyna, E Kochanowicz… - …, 2024 - Wiley Online Library
A novel library of naphthoquinone derivatives (3–5 aa) was synthesized and evaluated for
their anticancer properties. Specifically, compounds 5 i, 5 l, 5 o, 5 q, 5 r, 5 s, 5 t, and 5 v …
their anticancer properties. Specifically, compounds 5 i, 5 l, 5 o, 5 q, 5 r, 5 s, 5 t, and 5 v …
Synthesis and antiproliferative evaluation of some 1, 4-naphthoquinone derivatives against human cervical cancer cells
In the course of biological properties of quinone derivatives, the N (H)-, S-and S, S-
substituted-1, 4-naphthoquinones were synthesized by reactions of 2, 3-dichloro-1, 4 …
substituted-1, 4-naphthoquinones were synthesized by reactions of 2, 3-dichloro-1, 4 …
Synthesis of novel naphthoquinone aliphatic amides and esters and their anticancer evaluation
B Kongkathip, S Akkarasamiyo, K Hasitapan… - European journal of …, 2013 - Elsevier
Fourteen new naphthoquinone aliphatic amides and seventeen naphthoquinone aliphatic
esters were synthesized in nine to ten steps from 1-hydroxy-2-naphthoic acid with 9–25 …
esters were synthesized in nine to ten steps from 1-hydroxy-2-naphthoic acid with 9–25 …
Synthesis and anticancer evaluation of 1, 4‐naphthoquinone derivatives containing a phenylaminosulfanyl moiety
P Ravichandiran, SA Subramaniyan, SY Kim… - …, 2019 - Wiley Online Library
Naphthoquinones are exceptional building blocks in organic synthesis and have been used
to synthesize several well‐known pharmaceutically active agents. Herein we report the …
to synthesize several well‐known pharmaceutically active agents. Herein we report the …
Synthesis and cytotoxic evaluation of a series of 2-amino-naphthoquinones against human cancer cells
The cytotoxicity of a series of aminonaphthoquinones resulting from the reaction of suitable
aminoacids with 1, 4-naphthoquinone was assayed against SF-295 (glioblastoma), MDAMB …
aminoacids with 1, 4-naphthoquinone was assayed against SF-295 (glioblastoma), MDAMB …
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