New substituted 1, 4-naphthoquinones have been prepared in good overall yields through
the naphthol route. The cytotoxicity of these compounds was tested in vitro on MCF-7 breast …

Abstract Quinones such as 1, 4-naphthoquinones are abundant in nature and
naphthoquinone based natural products are known to possess anticancer activity. This …

In the present study substituted 1, 2-naphthoquinones were synthesized, purified and
characterized by spectroscopic studies (UV, FT-IR, 1 H NMR, 13 C NMR and elemental …

A novel library of naphthoquinone derivatives (3–5 aa) was synthesized and evaluated for
their anticancer properties. Specifically, compounds 5 i, 5 l, 5 o, 5 q, 5 r, 5 s, 5 t, and 5 v …

Sixteen novel naphthoquinone aromatic amides were synthesized by a new route starting
from 1-hydroxy-2-naphthoic acid in nine or ten steps with good to excellent yield. Amide …

Twelve novel naphthoquinone esters containing cyclopentyl and cyclohexyl substituents at
C-2′ of the propyl chain were synthesized by starting from 1-hydroxy-2-naphthoic acid via …

Naphthoquinones are exceptional building blocks in organic synthesis and have been used
to synthesize several well‐known pharmaceutically active agents. Herein we report the …

Introduction: A large number of natural products including several synthetic drugs possess
naphthoquinone chromophore. Various methods have been devised for their synthesis …

Cancer encompasses a group of pathologies with common characteristics, high incidence,
and prevalence in all countries. Although there are treatments available for this disease …

The cytotoxicity of a series of aminonaphthoquinones resulting from the reaction of suitable
aminoacids with 1, 4-naphthoquinone was assayed against SF-295 (glioblastoma), MDAMB …