Colorectal cancer (CRC) is the second most common cancer in women and the third most
common in men globally. CRC arises from one or a combination of chromosomal instability …

Originally, colorectal cancer (CRC) tumorigenesis was understood as a multistep process
that involved accumulation of tumor suppressor genes and oncogenes mutations, such as …

Colorectal cancer (CRC) results from the progressive accumulation of multiple genetic and
epigenetic aberrations within cells. The progression from colorectal adenoma to carcinoma …

Colorectal cancer (CRC) is the second most common newly diagnosed cancer and accounts
for the second highest number of cancer related deaths in Australia, the third worldwide and …

Research conducted during the past 30 years has increased our understanding of the
mechanisms involved in colorectal cancer initiation and development. The findings have …

Colorectal cancer (CRC) is the third most common cancer and the fourth most common
cause of cancer-related death. Most cases of CRC are detected in Western countries, with its …

This review explores the chief genetic and epigenetic events that promote pathological
progression in colorectal carcinogenesis. This article discusses the molecular and …

Cancer is currently among the leading causes of mortality globally. Colorectal cancer (CRC)
ranks second among the most common types of cancer in terms of mortality worldwide. This …

Colorectal cancer (CRC) is a heterogeneous disease, developing through a multipathway
sequence of events guided by clonal selections. Pathways included in the development of …

Colorectal cancer is a heterogeneous disease. There are three main pathways to colorectal
cancer: the chromosomal instability pathway, the CpG island methylator phenotype pathway …