… Transgenic mice with deletion of the GDF-9 (growth differentiation factor-9) gene are …
that GDF-9 is important for early follicle development, we isolated rat GDF-9 complementary …

… whole human ovaries that the GDF-9 protein is most abundantly … GDF-9-related factor,
GDF-9B, is coexpressed with GDF-9 during murine folliculogenesis. We now isolated human GDF-…

… Growth differentiation factor-9 is required during early … (EST) database with the mouse GDF-9
cDNA sequence, and … -β superfamily, and named it as GDF-9B. Northern blot hybridization …

… There has been a recent surge of interest in the role of growth differentiation factors and
other bone … the significance of growth and differentiation factor-9a (GDF-9a) and GDF-9b (bone …

… and differentiation factor 9 (GDF-9) in caprine ovarian follicles, and the effect of GDF-9 with
… To evaluate the expression of GDF-9 in Experiment 1, follicles were recovered from 32 goat …

… member, growth differentiation factor-9 (GDF-9), which is … GDF-9 messenger RNA is
synthesized only in the oocyte from … • Here we analyse ovaries from GDF9-deficient female mice …

… growth/differentiation factor-9 (GDF-9)] expressed specifically in the … GDF-9 is expressed
exclusively by oocytes. The oocyte specificity of GDF-9 is unique among known growth factor…

… These studies demonstrate that GDF-9 can bind to receptors on granulosa … and differentiation
factor during early folliculogenesis, GDF-9 functions as an oocyte-secreted paracrine factor …

… GDF-9 secreted by the oocyte is known to regulate the proliferation and differentiation of
granulosa cells (17). We hypothesized that GDF-9 shares receptors and downstream signaling …

… The paracrine signaling factors produced by the oocyte that … differentiation factor-9 (GDF-9)
secreted by the oocyte has been shown to play a key role in follicular development: GDF-9-…