… Here, we review DSB repair … of gene editing is revolutionizing both the basic and biomedical
sciences. The use of site-specific endonucleases for DSB repair studies and gene editing is …

… of clinical trials involving gene editing using clustered … In cancer immunotherapy, gene editing
is applied ex vivo in … ), E6 and E7 genes are disrupted using topically applied gene editing …

… breaks (DSBs) are produced intentionally by RNA-guided nucleases to achieve genome
editing through DSB repair… c-NHEJ-mediated DSB repair in gene editing and summarize the …

… -strand breaks generated by CRISPR/Cas9 and sgRNA are repaired by nonhomologous
end joining (NHEJ) or, in the presence of a donor template, by homology-directed repair (HDR). …

… or replace a gene using genome editing techniques such as … breaks (DSBs) by genome
editing tools can be repaired by … in imprecise repair. Scientists working at the crossroads of DNA …

… of the DNA repair circuitry, in conjunction with the rapid development of innovative genome
editing … pollution, develop cell-based therapies, and cure genetic and infectious diseases. …

… the genome, is revolutionizing our ability to decode the genome. Here we describe a simple
method for genome editing … of an efficient mechanism for gene conversion that utilizes linear …

… With assistance of fixing and repairing from NHEJ and HDR, CRISPR is able to edit any …
to a golden age of genetic editing. In the future, CRISPR and genetic editing will be applied to …

… , or gene deletions. Thus, the accuracy and efficiency of genome editing are influenced by the
cellular DSB repair … as such cells have evolved multiple mechanisms for their repair. These …

… with DSB repair represent a potential risk for human genome editing gene therapies. To …
-mediated horizontal gene transfer occurs in DSB repair during genome editing. Exosomes …