Macrophage differentiation-specific expression of NF-IL6, a transcription factor for interleukin-6

S Natsuka, S Akira, Y Nishio, S Hashimoto, T Sugita… - 1992 - ashpublications.org
… In this study, we show that NF-IL6 is upregulated during macrophage differentiation and …
macrophages, indicating that NF-IL6 is possibly an important transcription factor for macrophage

Identification of novel transcriptional regulators involved in macrophage differentiation and activation in U937 cells

YS Baek, S Haas, H Hackstein, G Bein… - BMC immunology, 2009 - Springer
… We report for the first time both mRNA and protein induction of MEF2 proteins, a MADS-box
transcription factor family, during macrophage differentiation and activation in U937 model …

Transcriptional regulation and macrophage differentiation

DA Hume, KM Summers, M Rehli - Myeloid Cells in Health and …, 2017 - Wiley Online Library
… the macrophage transcription factor PU.1, and the recognition motifs for basic helix-loop-helix
transcription factors of the microphthalmia transcription factor … in macrophages. TFEC is a …

Unimpaired macrophage differentiation and activation in mice lacking the zinc finger transcription factor NGFI-A (EGR1)

SL Lee, Y Wang, J Milbrandt - Molecular and cellular biology, 1996 - Am Soc Microbiol
… oligonucleotides prevent macrophage differentiation in HL-… differentiation and promotes
macrophage differentiation in HL-… -A deficiency on macrophage differentiation and function in …

MicroRNAs modulate the noncanonical transcription factor NF-κB pathway by regulating expression of the kinase IKKα during macrophage differentiation

T Li, MJ Morgan, S Choksi, Y Zhang, YS Kim… - Nature immunology, 2010 - nature.com
… cell differentiation. Here we show that during human monocyte-macrophage differentiation,
… , which led to higher expression of the serine-threonine kinase IKKα in macrophages. In …

Human monocyte-to-macrophage differentiation involves highly localized gain and loss of DNA methylation at transcription factor binding sites

KF Dekkers, AE Neele, JW Jukema, BT Heijmans… - Epigenetics & …, 2019 - Springer
Macrophages and their precursors monocytes play a key … Monocyte-to-macrophage
differentiation and activation … -to-macrophage differentiation occur at transcription factor binding …

The interplay between the master transcription factor PU. 1 and miR-424 regulates human monocyte/macrophage differentiation

A Rosa, M Ballarino, A Sorrentino… - Proceedings of the …, 2007 - National Acad Sciences
… We describe a pathway by which the master transcription factor PU.1 regulates human
monocyte/macrophage differentiation. This includes miR-424 and the transcriptional factor NFI-A. …

The zinc finger transcription factor Egr-1 is essential for and restricts differentiation along the macrophage lineage

HQ Nguyen, B Hoffman-Liebermann, DA Liebermann - Cell, 1993 - cell.com
… In the course of our work isolating Egr-7 cDNA from our PMA macrophage differentiation
-1, a zinc finger transcription factor, plays important roles in macrophage differentiation. The fact …

[PDF][PDF] Monocyte differentiation and macrophage polarization

AN Orekhov, VA Orekhova, NG Nikiforov… - Vessel Plus, 2019 - f.oaes.cc
… that stimulate macrophage differentiation [Figure 1][15]. Macrophages induced by both factors
have … In summary, the KLF family of transcription factors exhibits diverse effects on M1/M2 …

[HTML][HTML] Different pathways of macrophage activation and polarization

U Juhas, M Ryba-Stanisławowska, P Szargiej… - Advances in Hygiene …, 2015 - phmd.pl
… NF-κB is claimed to be a significant transcription factor, which regulates macrophage activation
… [43] discovered that macrophage differentiation factor CD11d can be regulated by KLF4. …