Emerging role of micro RNA s in regulating macrophage activation and polarization in immune response and inflammation

X Wu, Y Dai, Y Yang, C Huang, X Meng, B Wu… - Immunology, 2016 - Wiley Online Library
… Some studies have shown that miR-155 enhances classical macrophage activation by
repression of negative regulators of pro-inflammatory responses, including suppressor of cytokine …

MicroRNA-125b potentiates macrophage activation

AA Chaudhuri, AYL So, N Sinha… - The Journal of …, 2011 - journals.aai.org
… plays in regulating macrophage activation. We find that macrophages express a particularly
… When miR-125b is overexpressed in macrophages, it enhances surface activation markers …

[HTML][HTML] MicroRNAs as molecular switches in macrophage activation

G Curtale, M Rubino, M Locati - Frontiers in immunology, 2019 - frontiersin.org
… in the regulation of macrophage activation and polarization. miRNAs affect macrophage
activation and … Differential expression of miRNAs in macrophages also modulates macrophage

MicroRNA regulated macrophage activation in obesity

C Li, L Qu, C Farragher, A Vella… - Journal of translational …, 2019 - degruyter.com
… [29] However, the role of extracellular RNAs in regulating macrophage activation
miRNA-regulated macrophage activation in obesity originates from the complex nature of …

Suppression of microRNA activity amplifies IFN-γ-induced macrophage activation and promotes anti-tumour immunity

C Baer, ML Squadrito, D Laoui, D Thompson… - Nature cell …, 2016 - nature.com
… Here we show that conditional deletion of the microRNA (miRNA)-processing enzyme
DICER in macrophages prompts M1-like TAM programming, characterized by hyperactive IFN-γ/…

MicroRNA-487b is a negative regulator of macrophage activation by targeting IL-33 production

Y Xiang, F Eyers, C Herbert, HL Tay… - The Journal of …, 2016 - journals.aai.org
macrophage differentiation and activation. We demonstrate that miR-487b is negative regulator
of macrophage activation … bone marrow (BM)-derived macrophages (BMDMs), it played a …

The microRNA-342-5p Fosters Inflammatory Macrophage Activation Through an Akt1- and microRNA-155–Dependent Pathway During Atherosclerosis

Y Wei, M Nazari-Jahantigh, L Chan, M Zhu, K Heyll… - Circulation, 2013 - Am Heart Assoc
… of macrophages. Therefore, we hypothesized a role for miR-342-5p in macrophage activation
-342-5p promotes the proinflammatory activation of macrophages by enhancing nitric oxide …

MicroRNA-mediated control of macrophages and its implications for cancer

ML Squadrito, M Etzrodt, M De Palma, MJ Pittet - Trends in immunology, 2013 - cell.com
… (miRNAs) implicated in macrophage development and activation. Defined miRNAs control
… (at steady-state), and/or control macrophage activation. The induction of miRNAs is context-…

MiRNA-mediated macrophage polarization and its potential role in the regulation of inflammatory response

K Essandoh, Y Li, J Huo, GC Fan - Shock, 2016 - journals.lww.com
miRNA expression profiles in polarized macrophages from murine and human sources, and
summarizes how these miRNAs regulate macrophage … Classical activation of macrophages

MicroRNA-155 is induced during the macrophage inflammatory response

RM O'Connell, KD Taganov… - Proceedings of the …, 2007 - National Acad Sciences
… Similar to IFN-β, IFN-γ is produced in response to viral and bacterial infections and plays
an important role in macrophage activation (32). IFN-γ also induced miR-155 in macrophages