Preclinical safety of solid lipid nanoparticles and nanostructured lipid carriers: Current evidence from in vitro and in vivo evaluation
… safety. After 25 years of research on SLN and NLC, enough evidence on their preclinical safety
… Here, we provide an update on available data from preclinical in vitro testing, reported in …
… Here, we provide an update on available data from preclinical in vitro testing, reported in …
Preclinical safety of topically administered nanostructured lipid carriers (NLC) for wound healing application: biodistribution and toxicity studies
C Vairo, M Collantes, G Quincoces, S Villullas… - International journal of …, 2019 - Elsevier
Re-activation of the healing process is a major challenge in the field of chronic wound
treatment. For that purpose, lipid-nanoparticles, especially nanostructured lipid carriers (NLC), …
treatment. For that purpose, lipid-nanoparticles, especially nanostructured lipid carriers (NLC), …
Lipid-based carriers for pulmonary products: preclinical development and case studies in humans
D Cipolla, B Shekunov, J Blanchard… - Advanced drug delivery …, 2014 - Elsevier
… lipid microparticles, many of which are porous in nature, liposomes, solid lipid nanoparticles
and nanostructured lipid carriers… of these systems, the safety of these lipid-based systems in …
and nanostructured lipid carriers… of these systems, the safety of these lipid-based systems in …
[HTML][HTML] Preclinical assessment of ursolic acid loaded into nanostructured lipid carriers in experimental visceral leishmaniasis
JA Jesus, IMO Sousa, TNF da Silva, AF Ferreira… - Pharmaceutics, 2021 - mdpi.com
… Among the different drug delivery systems, nanostructured lipid carriers (NLCs) are one of
the most studied and show attractive attributes meeting the requirements of an ideal carrier …
the most studied and show attractive attributes meeting the requirements of an ideal carrier …
Nanostructured lipid carriers: Promising drug delivery systems for future clinics
… The understanding of the nanostructured lipid carriers (NLC)-based formulations has improved
… challenges in the use of nanostructured lipid carriers as controlled drug delivery systems. …
… challenges in the use of nanostructured lipid carriers as controlled drug delivery systems. …
Improvement of drug safety by the use of lipid-based nanocarriers
SB Lim, A Banerjee, H Önyüksel - Journal of controlled release, 2012 - Elsevier
… More recently, modifications of SLN have been undertaken to produce second generation
SLN known as the nanostructured lipid carriers (NLC) and the lipid drug conjugates (LDC). …
SLN known as the nanostructured lipid carriers (NLC) and the lipid drug conjugates (LDC). …
Nanostructured lipid carriers-based drug delivery for treating various lung diseases: A State‐of‐the‐Art Review
TS Patil, AS Deshpande - International journal of pharmaceutics, 2018 - Elsevier
… The present review draws attention to the foundational concepts of the selected carrier
system, ie nanostructured lipid carriers (NLCs), its advantages over other nanocarrier systems, …
system, ie nanostructured lipid carriers (NLCs), its advantages over other nanocarrier systems, …
Nanostructured Lipid Carriers for oral treatment of leishmaniasis: Design and preclinical evaluation
ML de Souza, VAW Sales, SG dos Santos Sales… - Colloids and Surfaces A …, 2024 - Elsevier
… In this context, this research aimed to develop nanostructured lipid carriers containing
meglumine antimoniate to obtain a possible oral therapeutic alternative for leishmaniasis. To …
meglumine antimoniate to obtain a possible oral therapeutic alternative for leishmaniasis. To …
Nanostructured lipid carriers for improved delivery of therapeutics via the oral route
… , nanostructured lipid carriers (NLCs) have emerged as a promising delivery carrier that can
… This review explores the diverse applications of nanostructured lipid carriers (NLCs) in oral …
… This review explores the diverse applications of nanostructured lipid carriers (NLCs) in oral …
Safety and effectiveness of sodium colistimethate-loaded nanostructured lipid carriers (SCM-NLC) against P. aeruginosa: in vitro and in vivo studies following …
M Pastor, J Basas, C Vairo, G Gainza… - … , Biology and Medicine, 2019 - Elsevier
… Further studies are required for the preclinical development of the lipid nanoparticle, but
this work provides an early proof of the effectiveness and non-toxicity of SCM-NLC, under …
this work provides an early proof of the effectiveness and non-toxicity of SCM-NLC, under …
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