Reflection and Reaction 574 http://neurology. thelancet. com Vol 6 July 2007 of limited data.
Kenet, Kirkham, and colleagues have given paediatric neurologists guidance on how to …

Stroke in children differs from stroke in adults in many ways, with a high occurrence of
haemorrhage and a rarity of established atherosclerosis seen in children. A new set of …

Objective: To characterize long-term mortality following intracerebral hemorrhage (ICH) in
two large population-based cohorts assembled more than a decade apart. Methods: All …

Advances in patient care follow a typical sequence of events—preclinical research followed
by studies in healthy volunteers and then in patients with the target disorder. Definitive …

For cerebral sinovenous thrombosis without evidence of haemorrhage on parenchymal
neuroimaging, there was an agreement among all guidelines to treat older children (non …

Objective To assess the use of anticoagulant therapy in a consecutive cohort study of
children with sinovenous thrombosis (SVT). Methods A single institutional pilot study of …

Anticoagulant therapy to prevent non-cardioembolic ischaemic stroke is not a novel
approach; its use dates back to the 1950s. However, by the 1990s, randomised trials …

Background Cerebral sinovenous thrombosis in children is a serious disorder, and
information is needed about its prevention and treatment. Methods The Canadian Pediatric …

Evidence at the population level shows that giving oral anticoagulants has a clear long-term
benefit in preventing recurrent ischaemic stroke in people with ischaemic stroke and atrial …

Thrombosis plays an important part in acute ischaemic stroke, and antithrombotic therapies
are a logical approach to treatment. Heparin has been advocated for acute stroke since the …