OBJECTIVE: Adolescence is a developmental period that entails substantial changes in risk-
taking behavior and experimentation with alcohol and drugs. Understanding how the brain …

OBJECTIVE: Epidemiological studies indicate that experimentation with addictive drugs and
onset of addictive disorders is primarily concentrated in adolescence and young adulthood …

The likelihood of initiating addictive behaviors is higher during adolescence than during any
other developmental period. The differential developmental trajectories of brain regions …

In adolescents, alcohol interacts extensively with reward neurocircuitry and corticolimbic
structure and function in ways that promote maladaptive behaviors that lead to addiction …

Psychoactive substance and nonsubstance/behavioral addictions are major public health
concerns associated with significant societal cost. Adolescence is a period of dynamic …

Background Adolescence represents a period of development during which critical
biological, as well as social and cognitive, changes occur that are necessary for the …

The purpose of this review is to summarize the neurobiological factors involved in the
etiology of adolescent addiction and present evidence implicating various mechanisms in its …

Magnetic resonance (MR) techniques provide opportunities to non-invasively characterize
neurobiological milestones of adolescent brain development. Juxtaposed to the critical …

Adolescence is a developmental period characterized by suboptimal decisions and actions
that give rise to an increased incidence of unintentional injuries and violence, alcohol and …

The transition to adolescence is characterized by rapid biological transformations that
include not only the hormonal and physiological changes of puberty but also dramatic …