Background Morbidity in COPD results from a combination of factors including hypoxia-
induced pulmonary hypertension, in part due to pulmonary vascular remodelling. Animal …

Pulmonary hypertension (PH) is an important complication in the natural history of chronic
obstructive pulmonary disease (COPD). Its presence is associated with reduced survival and …

Abstract Objectives: Angiotensin II (ANG II) is known to be a potent vasoconstrictor agent in
the pulmonary circulation. Furthermore, type 1 ANG II receptor blockade with losartan …

Pulmonary hypertension is a common complication of chronic obstructive pulmonary
disease (COPD). Its presence is associated with shorter survival and worse clinical …

Even mild pulmonary hypertension (PH) is associated with increased mortality and morbidity
in patients with chronic obstructive pulmonary disease (COPD). However, the underlying …

In chronic respiratory diseases, especially chronic obstructive pulmonary disease (COPD)
pulmonary arterial hypertension is generally mild to moderate and the necessity for treating …

Purpose Pulmonary hypertension (PH) due to COPD has dismal prognosis. We reviewed
the long-term effect of PH-target therapy in severe PH-COPD. Method Patients attending our …

The recent findings summarized here have expanded our knowledge regarding this
important comorbidity in patients with advanced COPD. We now know that pulmonary …

The possibility that pulmonary hypertension (PH) may develop in patients with chronic
obstructive pulmonary disease (COPD) is well established, but prevalence data vary. The …

The development of pulmonary hypertension is a poor prognostic sign in patients with
chronic obstructive pulmonary disease (COPD), affecting both mortality and quality of life …