Diversity and plasticity are hallmarks of macrophages. Classically activated macrophages
are considered to promote T helper type 1 responses and have strong microbicidal, pro …

Diversity and plasticity are the hallmarks of cells from the monocyte–macrophage lineage.
Macrophages undergo classical M1 or alternative M2 activation in response to the …

The ability of a healthy immune system to clear the plethora of antigens it encounters
incessantly relies on the enormous plasticity displayed by the comprising cell types …

Inflammation is essential to combat invading microbial pathogens. In this process, the
involvement of multiple immune cell populations is crucial in mounting an optimum immune …

microRNAs (miRNAs) are small noncoding RNAs that regulate gene expression at a
posttranscriptional level and play a crucial role in the development of cells of the immune …

Macrophages are key cells of the innate immune system with functional roles in both
homeostatic maintenance of self-tissues and inflammatory responses to external stimuli …

Macrophages are known to have an impact in cytokine signaling in the myriad of organs in
which they reside and are classically known to be either pro-inflammatory (M1), anti …

Much has been learned about the molecular and cellular components critical for the control
of immune responses and tolerance. It remains a challenge, however, to control the immune …

Macrophages respond to external stimuli with rapid changes in expression of many genes.
Different combinations of external stimuli lead to distinct polarized activation patterns …

Micro RNA s (mi RNA s) have emerged as important regulators of gene expression in
diverse biological processes ranging from cell proliferation and survival to organ …