Macrophages (Mϕ) are an important component of the innate immune system; they play
critical roles in the first line of defense to pathogen invasion and modulate adaptive …

Monocytes/macrophages respond to external stimuli with rapid changes in the expression of
numerous inflammation-related genes to undergo polarisation towards the M1 (pro …

Abstract MicroRNAs (miRNAs) are about 20–22 nucleotide conserved non-coding RNA
molecules that post-transcriptionally regulate gene expression by targeting the 3 …

MicroRNAs (miRNAs) are an abundant class of small noncoding RNA molecules that play
an important role in the regulation of gene expression at the posttranscriptional level. Due to …

Micro RNA s, small non‐coding RNAs expressed by eukaryotic cells, play pivotal roles in
shaping cell differentiation and organism development. Deregulated micro RNA expression …

To secure the functionality of activated macrophages in the innate immune response,
efficient life span control is required. Recognition of bacterial lipopolysaccharides (LPS) by …

Inflammation is a host defense mechanism orchestrated through imperative factors-acute
inflammatory responses mediated by cellular and molecular events leading to activation of …

MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression by binding
to complementary target mRNAs and either promoting their decay or inhibiting their …

Mucosal surface epithelial cells are equipped with several defense mechanisms that guard
against pathogens. Recent studies indicate that microRNAs (miRNAs) mediate post …

Polarization of macrophages is regulated through complex signaling networks. Correlating
miRNA and mRNA expression over time after macrophage polarization has not yet been …