At present, single-chain variable fragments (scFv) of antibodies are considered one of the
most important tools in human therapies. Wide applications of antibodies are being …

Background Due to their unique ability to bind their targets with high fidelity, antibodies are
used widely not only in biomedical research, but also in many clinical applications …

Multivalency is one of the hallmarks of antibodies, by which enormous gains in functional
affinity, and thereby improved performance in vivo and in a variety of in vitro assays are …

With 18 monoclonal antibody (mAb) products currently on the market and more than 100 in
clinical trials, it is clear that engineered antibodies have come of age as biopharmaceuticals …

The interest in the use of monoclonal antibodies as therapeutic molecules has raised in the
recent years. Due to their high affinity and specificity towards other biological molecules …

Engineered antibodies are key players in therapy, diagnostics and research. In addition to
full size immunoglobulin gamma (IgG) molecules, smaller formats of recombinant …

Development trends for therapeutic antibody fragments | Nature Biotechnology Skip to main
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Background Antibodies have been a pillar of basic research, while their relevance in clinical
diagnostics and therapy is constantly growing. Consequently, the production of both …

Antibodies (Abs) are some of the most powerful tools in therapy and diagnostics and are
currently one of the fastest growing classes of therapeutic molecules. Recombinant antibody …

Antibody fragments are used in the clinic as important therapeutic proteins for treatment of
indications where better tissue penetration and less immunogenic molecules are needed …