Signaling pathways and therapeutic interventions in gastric cancer

ZN Lei, QX Teng, Q Tian, W Chen, Y Xie… - Signal transduction and …, 2022 - nature.com
Gastric cancer (GC) ranks fifth in global cancer diagnosis and fourth in cancer-related death.
Despite tremendous progress in diagnosis and therapeutic strategies and significant …

[HTML][HTML] Molecular classification of gastric cancer: Towards a pathway-driven targeted therapy

I Riquelme, K Saavedra, JA Espinoza, H Weber… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Gastric cancer (GC) is the third leading cause of cancer mortality worldwide. Although
surgical resection is a potentially curative approach for localized cases of GC, most cases of …

Gastric cancer in the era of molecularly targeted agents: current drug development strategies

HT Arkenau - Journal of cancer research and clinical oncology, 2009 - Springer
Gastric cancer is the second most common cause of cancer death worldwide with
approximately one million cases diagnosed annually. Despite considerable improvements …

Molecular pathogenesis, targeted therapies, and future perspectives for gastric cancer

Y Zeng, RU Jin - Seminars in cancer biology, 2022 - Elsevier
Gastric cancer is a major source of global cancer mortality with limited treatment options and
poor patient survival. As our molecular understanding of gastric cancer improves, we are …

[HTML][HTML] Biomarkers of gastric cancer: Current topics and future perspective

T Matsuoka, M Yashiro - World journal of gastroenterology, 2018 - ncbi.nlm.nih.gov
Gastric cancer (GC) is one of the most prevalent malignant types in the world and an
aggressive disease with a poor 5-year survival. This cancer is biologically and genetically …

Targeted therapy for gastric cancer: molecular pathways and ongoing investigations

W Yang, A Raufi, SJ Klempner - … et Biophysica Acta (BBA)-Reviews on …, 2014 - Elsevier
Gastric cancer is currently the second leading cause of worldwide cancer mortality. Ongoing
collaborative sequencing efforts have highlighted recurrent somatic genomic aberrations in …

Gastric cancer—molecular and clinical dimensions

R Wadhwa, S Song, JS Lee, Y Yao, Q Wei… - Nature reviews Clinical …, 2013 - nature.com
Gastric cancer imposes a considerable health burden around the globe despite its declining
incidence. The disease is often diagnosed in advanced stages and is associated with a poor …

Gastric cancer: a comprehensive review of current and future treatment strategies

RE Sexton, MN Al Hallak, M Diab, AS Azmi - Cancer and Metastasis …, 2020 - Springer
Gastric cancer remains a major unmet clinical problem with over 1 million new cases
worldwide. It is the fourth most commonly occurring cancer in men and the seventh most …

[HTML][HTML] Gastric cancer in the era of precision medicine

X Liu, SJ Meltzer - Cellular and molecular gastroenterology and …, 2017 - Elsevier
Gastric cancer (GC) remains the third most common cause of cancer death worldwide, with
limited therapeutic strategies available. With the advent of next-generation sequencing and …

Comparison and applicability of molecular classifications for gastric cancer

O Serra, M Galán, MM Ginesta, M Calvo, N Sala… - Cancer treatment …, 2019 - Elsevier
Gastric Cancer (GC) is a complex and heterogeneous disease, which represents a global
health concern. Despite advances in prevention, diagnosis, and therapy, GC is still a leading …