Generalized cell morphological parameters based on interferometric phase microscopy and their application to cell life cycle characterization

P Girshovitz, NT Shaked - Biomedical optics express, 2012 - opg.optica.org
We present analysis tools which are formulated using wide-field interferometric phase
microscopy measurements, and show their ability to uniquely quantify the life cycle of live …

Dual-interference-channel quantitative-phase microscopy of live cell dynamics

NT Shaked, MT Rinehart, A Wax - Optics letters, 2009 - opg.optica.org
We introduce and experimentally demonstrate a fast and accurate method for quantitative
imaging of the dynamics of live biological cells. Using a dual-channel interferometric setup …

Quantitative phase microscopy spatial signatures of cancer cells

D Roitshtain, L Wolbromsky, E Bal… - Cytometry Part …, 2017 - Wiley Online Library
We present cytometric classification of live healthy and cancerous cells by using the spatial
morphological and textural information found in the label‐free quantitative phase images of …

Optical detection and measurement of living cell morphometric features with single-shot quantitative phase microscopy

P Bon, J Savatier, M Merlin… - … of biomedical optics, 2012 - spiedigitallibrary.org
We present a quadriwave lateral shearing interferometer used as a wavefront sensor and
mounted on a commercial non-modified transmission white-light microscope as a …

Two-step-only phase-shifting interferometry with optimized detector bandwidth for microscopy of live cells

NT Shaked, Y Zhu, MT Rinehart, A Wax - Optics Express, 2009 - opg.optica.org
We present a phase-shifting interferometric technique for imaging live biological cells in
growth media, while optimizing spatial resolution and enabling potential real-time …

High-precision microscopic phase imaging without phase unwrapping for cancer cell identification

E Watanabe, T Hoshiba, B Javidi - Optics Letters, 2013 - opg.optica.org
Experiments for cell identification are presented using a high-precision cell phase
measurement system that does not require any phase unwrapping. This system is based on …

Quantitative phase microscopy of biological samples using a portable interferometer

NT Shaked - Optics letters, 2012 - opg.optica.org
This Letter presents the τ interferometer, a portable and inexpensive device for obtaining
spatial interferograms of microscopic biological samples without the strict stability and the …

Diffraction phase and fluorescence microscopy

YK Park, G Popescu, K Badizadegan, RR Dasari… - Optics express, 2006 - opg.optica.org
We have developed diffraction phase and fluorescence (DPF) microscopy as a new
technique for simultaneous quantitative phase imaging and epi-fluorescence investigation of …

Optical‐mechanical signatures of cancer cells based on fluctuation profiles measured by interferometry

Y Bishitz, H Gabai, P Girshovitz… - Journal of …, 2014 - Wiley Online Library
We propose to establish a cancer biomarker based on the unique optical‐mechanical
signatures of cancer cells measured in a noncontact, label‐free manner by optical …

Quantitative phase imaging of live cells using fast Fourier phase microscopy

N Lue, W Choi, G Popescu, T Ikeda, RR Dasari… - Applied Optics, 2007 - opg.optica.org
Using the decomposition of an image field in two spatial components that can be
controllably shifted in phase with respect to each other, a new quantitative-phase …