Background Use of tranexamic acid (TXA) is effective and safe in reducing the blood loss in
total knee arthroplasty (TKR) performed using a tourniquet, but, data in TKR performed …

Background Tranexamic acid (TXA) is widely used in the orthopedic field and particularly in
total knee arthroplasty (TKA). Its efficacy and safety in reducing the blood loss in TKA have …

Abundant literature confirms that intravenous (IV) and intra-articular (IA) administration of
tranexamic acid (TXA) reduces blood loss in total knee arthroplasty (TKA). Oral formulations …

Purpose This meta-analysis was designed to compare the effectiveness and safety of
intravenous (IV) versus topical administration of tranexamic acid (TXA) in patients …

Purpose Tranexamic acid (TXA) has been shown to be effective in reducing blood loss after
total knee replacement. The purpose of this study was to prospectively assess the …

Background Although randomized controlled trials have confirmed oral tranexamic acid
(TXA) can provide similar blood-sparing efficacy compared with intravenous (IV) TXA in total …

Background: Tranexamic acid (TXA) reduces bleeding and the need for transfusion after
total knee arthroplasty. Most literature has focused on intravenous (IV) administration of TXA …

Methods: We performed a prospective randomized controlled trial (1: 1 fashion) on the use
of tranexamic acid versus placebo in 50 patients undergoing TKA (without tourniquet). The …

Background The combined administration of intravenous (IV) and topical tranexamic acid
(TXA) in primary total knee (TKA) knee remains controversial. The purpose of this meta …

Introduction The aim of this study was to examine whether the administration of multiple
boluses of oral or intravenous tranexamic acid (TXA) postoperatively were equivalent at …