Previously we reported that the variable heavy chain region (VH) of a human beta 2
glycoprotein I-dependent monoclonal antiphospholipid antibody (IS4) was dominant in …

Autoantibodies in systemic lupus erythematosus react with multiple epitopes on highly
conserved molecules such as nucleic acids, cytoskeletal proteins, phospholipids, and …

Objective Thromboembolic manifestations or thrombocytopenia in association with
anticardiolipin antibodies (aCL) or lupus anticoagulant are known as the antiphospholipid …

Objective To test the feasibility of applying a mimetic (specific for a patient‐derived
prothrombotic anticardiolipin antibody [aCL]) to study the homologous, disease‐associated …

Research on antiphospholipid antibodies (aPL) and the thrombotic manifestations
associated with these antibodies has grown almost logarithmically since the description of …

Of 164 sera with antinucleolar antibodies, 7 (4.3%) were shown by Western blotting to react
with a 37‐kd polypeptide in a nuclear extract of HeLa cells and with the recombinant protein …

Anti-double-stranded DNA antibodies (anti-dsDNA) and antiphospholipid antibodies (APL)
are important in the pathogenesis of systemic lupus erythematosus (SLE) and the …

Human β2-glycoprotein I (β2-GPI) is involved in cardiolipin (CL) binding of anticardiolipin
antibodies (aCL) in systemic lupus erythematosus (SLE). We examined the inter-species …

beta 2-Glycoprotein I (beta 2-GPI), a phospholipid-binding plasma protein, is an absolute
requirement (cofactor) for the binding of autoimmune-type anti-cardiolipin (aCL) antibodies …

We have recently shown that cardiolipin (CL) and its metabolites move from mitochondria to
other cellular membranes during death receptor-mediated apoptosis. In this study, we …