[HTML][HTML] MicroRNAs: as critical regulators of tumor-associated macrophages

B Chatterjee, P Saha, S Bose, D Shukla… - International journal of …, 2020 - mdpi.com
Emerging shreds of evidence suggest that tumor-associated macrophages (TAMs) modulate
various hallmarks of cancer during tumor progression. Tumor microenvironment (TME) …

MicroRNAs in tumor immunity: functional regulation in tumor-associated macrophages

C Chen, J Liu, Y Luo - Journal of Zhejiang University-Science B, 2020 - Springer
Tumor-associated macrophages (TAMs) are the most abundant immune cells in the tumor
microenvironment (TME) and are critical for cancer initiation and progression. MicroRNAs …

[HTML][HTML] Crosstalk between tumor-associated macrophages and MicroRNAs: a key role in tumor microenvironment

X Zhou, B Chen, Z Zhang, Y Huang, J Li, Q Wei… - International Journal of …, 2022 - mdpi.com
As an in-depth understanding of immunotherapy continues to grow, current anticancer
therapy research is increasingly focused on the tumor microenvironment (TME). MicroRNAs …

[HTML][HTML] Microrna—A tumor trojan horse for tumor-associated macrophages

SN Syed, AC Frank, R Raue, B Brüne - Cells, 2019 - mdpi.com
MicroRNAs (miRs) significantly contribute to the regulation of gene expression, by virtue of
their ability to interact with a broad, yet specific set of target genes. MiRs are produced and …

[HTML][HTML] MicroRNAs: pleiotropic regulators in the tumor microenvironment

N Yang, S Zhu, X Lv, Y Qiao, YJ Liu… - Frontiers in immunology, 2018 - frontiersin.org
MicroRNAs (miRNAs) are small non-coding RNAs that typically inhibit the translation and
stability of messenger RNAs (mRNAs). They are~ 22 nucleotides long and control both …

MicroRNA-mediated control of macrophages and its implications for cancer

ML Squadrito, M Etzrodt, M De Palma, MJ Pittet - Trends in immunology, 2013 - cell.com
Deregulation of microRNAs (miRNAs) can drive oncogenesis, tumor progression, and
metastasis by acting cell-autonomously in cancer cells. However, solid tumors are also …

Exploring and exploiting the fundamental role of microRNAs in tumor pathogenesis

Q Cheng, X Jiang - OncoTargets and therapy, 2013 - Taylor & Francis
miRNAs (miRs) are short RNA molecules that are involved in the posttranscriptional
regulation of mRNA. The roles of miRs in tumor pathogenesis have only recently become a …

The impact of microRNAs on myeloid-derived suppressor cells in cancer

S Noorolyai, PHG Duijf, N Silvestris, S Kolahian… - Human Immunology, 2021 - Elsevier
Inflammation promotes cancer development. To a large extent, this can be attributed to the
recruitment of myeloid-derived suppressor cells (MDSCs) to tumors. These cells are known …

[HTML][HTML] MicroRNAs as molecular switches in macrophage activation

G Curtale, M Rubino, M Locati - Frontiers in immunology, 2019 - frontiersin.org
The efficacy of macrophage-mediated inflammatory response relies on the coordinated
expression of key factors, which expression is finely regulated at both transcriptional and …

[HTML][HTML] Identification of the microRNA networks contributing to macrophage differentiation and function

H Zhou, J Zhang, F Eyers, Y Xiang, C Herbert, HL Tay… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Limited evidence is available about the specific miRNA networks that regulate differentiation
of specific immune cells. In this study, we characterized miRNA expression and associated …