111In-pentetreotide scintigraphy versus 68Ga-DOTATATE PET: impact on Krenning scores and effect of tumor burden

TA Hope, J Calais, L Zhang… - Journal of Nuclear …, 2019 - Soc Nuclear Med
Eligibility for somatostatin receptor (SSTR) radionuclide therapy uses the qualitative
Krenning score based on 111In-pentetreotide planar scintigraphy as was performed in the …

[HTML][HTML] Molecular imaging radiotherapy: theranostics for personalized patient management of neuroendocrine tumors (NETs)

K Öberg - Theranostics, 2012 - ncbi.nlm.nih.gov
Neuroendocrine tumors (NETs) possess unique features including expression of peptide
hormone receptors as well as the capacity to concentrate and take up precursor forms of …

Impact of initial imaging with gallium‐68 dotatate PET/CT on diagnosis and management of patients with neuroendocrine tumors

A Crown, FG Rocha, P Raghu, B Lin… - Journal of surgical …, 2020 - Wiley Online Library
Background Somatostatin analog functional imaging with gallium‐68 (Ga‐68) dotatate
positron emission tomography/computed tomography (PET/CT) has demonstrated …

Evaluating the clinical effectiveness of 90Y-SMT 487 in patients with neuroendocrine tumors

D Bushnell, T O'Dorisio, Y Menda… - Journal of Nuclear …, 2003 - Soc Nuclear Med
Because of the presence of cell membrane somatostatin receptors (SSTRs), many
neuroendocrine tumors will bind analogs of somatostatin. 90Y-Dodecanetetraacetic acid …

Inferior outcome of neuroendocrine tumor patients negative on somatostatin receptor imaging

J Refardt, WT Zandee, T Brabander… - Endocrine-related …, 2020 - erc.bioscientifica.com
Sufficient expression of somatostatin receptor (SSTR) in well-differentiated neuroendocrine
tumours (NETs) is crucial for treatment with somatostatin analogues (SSAs) and peptide …

Gene transcript analysis blood values correlate with 68Ga-DOTA-somatostatin analog (SSA) PET/CT imaging in neuroendocrine tumors and can define disease …

L Bodei, M Kidd, IM Modlin, V Prasad, S Severi… - European journal of …, 2015 - Springer
Purpose Precise determination of neuroendocrine tumor (NET) disease status and response
to therapy remains a rate-limiting concern for disease management. This reflects limitations …

225Ac-MACROPATATE: a novel α-particle peptide receptor radionuclide therapy for neuroendocrine tumors

AP King, NT Gutsche, N Raju, S Fayn… - Journal of Nuclear …, 2023 - Soc Nuclear Med
Neuroendocrine tumors (NETs) express somatostatin receptors (SSTRs) 2 and 5. Modified
variants of somatostatin, the cognate ligand for SSTR2 and SSTR5, are used in treatment for …

Molecular imaging and therapy of somatostatin receptor positive tumors

J Ivanidze, M Roytman, A Sasson, M Skafida… - Clinical Imaging, 2019 - Elsevier
Somatostatin receptors (SSTR) are upregulated in the cells of origin that define numerous
neuroendocrine neoplasms. PET imaging with 68 Ga-DOTATATE allows specific targeting of …

Imaging of Neuroendocrine Neoplasms: Monitoring Treatment Response—AJR Expert Panel Narrative Review

SJ Galgano, A Iravani, L Bodei… - American Journal of …, 2022 - Am Roentgen Ray Soc
Neuroendocrine neoplasms (NENs) encompass a broad spectrum of tumors throughout the
body and range in biologic behavior from indolent to aggressive. Consequently, a wide …

68Ga-DOTA-Tyr3-octreotide PET in neuroendocrine tumors: comparison with somatostatin receptor scintigraphy and CT

M Gabriel, C Decristoforo, D Kendler… - Journal of nuclear …, 2007 - Soc Nuclear Med
The aim of this study was to evaluate the diagnostic value of a new somatostatin analog,
68Ga-labeled 1, 4, 7, 10-tetraazacyclododecane-N, N′, N ″, N ″′-tetraacetic acid-d …