Hypoxic pulmonary hypertension in man: what minimum daily duration of hypoxaemia is required?

E Weitzenblum, A Chaouat - European Respiratory Journal, 2001 - Eur Respiratory Soc
It is recognized that chronic alveolar hypoxia is the major cause of pulmonary hypertension
in chronic respiratory diseases [1]. Accordingly, this form of secondary pulmonary …

Pulmonary hypertension in obstructive sleep apnoea

L Laks, B Lehrhaft, RR Grunstein… - European Respiratory …, 1995 - Eur Respiratory Soc
To determine the frequency and correlates of pulmonary hypertension in sleep-disordered
breathing, pulmonary artery pressure, lung function and arterial blood gases were measured …

“Natural history” of pulmonary hypertension in a series of 131 patients with chronic obstructive lung disease

R Kessler, M Faller, E Weitzenblum… - American journal of …, 2001 - atsjournals.org
The prognostic value and the evolution of pulmonary hypertension (PH) in patients with
markedly hypoxemic chronic obstructive pulmonary disease (COPD), treated or not with long …

Nocturnal hypoxemia is common in primary pulmonary hypertension

AL Rafanan, JA Golish, DS Dinner, LK Hague… - Chest, 2001 - Elsevier
Study objective Unsuspected sleep-related respiratory events are common in patients with
severe pulmonary disease. Sleep in patients with primary pulmonary hypertension (PPH) …

Effects of intermittent hypoxia on pulmonary haemodynamics: animal models versus studies in humans

J Zieliński - European Respiratory Journal, 2005 - Eur Respiratory Soc
The aim of this review was to analyse the effects of intermittent hypoxia (IH) on pulmonary
haemodynamics, comparing results of animal experiments with results of clinical studies. In …

Evolution and prognosis of pulmonary hypertension in chronic obstructive pulmonary diseases.

E Weitzenblum, M Mammosser, M Ehrhart - Herz, 1986 - europepmc.org
The prognostic value of the presence and degree of pulmonary arterial hypertension (PAH)
in chronic obstructive pulmonary diseases (COPD) has been well established by recent …

Nocturnal pulmonary hypertension in patients with chronic obstructive pulmonary disease

PG Boysen, AJ Block, JW Wynne, LA Hunt, MR Flick - Chest, 1979 - Elsevier
Oxygen desaturation occurs during sleep in some patients with COPD. To investigate the
effects of these hypoxemic episodes on the pulmonary vasculature, we studied four patients …

Sleep-related O2 desaturation and daytime pulmonary haemodynamics in COPD patients with mild hypoxaemia

A Chaouat, E Weitzenblum, R Kessler… - European …, 1997 - Eur Respiratory Soc
It has been hypothesized but not firmly established that sleep-related hypoxaemia could
favour the development of pulmonary hypertension in chronic obstructive pulmonary …

Acute and chronic hypoxic pulmonary hypertension.

T Higenbottam, G Cremona - The European respiratory journal, 1993 - europepmc.org
The development of secondary pulmonary hypertension (PH) as a result of pulmonary
disease, both in adults and children, considerably worsens prognosis. Chronic hypoxia …

Outcome of COPD patients with mild daytime hypoxaemia with or without sleep-related oxygen desaturation

A Chaouat, E Weitzenblum, R Kessler… - European …, 2001 - Eur Respiratory Soc
The aim of the present study was to compare the evolution of pulmonary haemodynamics
and of arterial blood gases in chronic obstructive pulmonary disease (COPD) patients with …