Insulin-like growth factor I regulates gonadotropin responsiveness in the murine ovary

J Zhou, TR Kumar, MM Matzuk… - Molecular …, 1997 - academic.oup.com
The present study shows that insulin-like growth factor I (IGF-I) and FSH receptor (FSHR)
mRNAs are selectively coexpressed in a subset of healthy-appearing follicles in murine …

FSH regulates IGF-2 expression in human granulosa cells in an AKT-dependent manner

SC Baumgarten, SM Convissar… - The Journal of …, 2015 - academic.oup.com
Context: IGF-2 is highly expressed in the granulosa cells of human dominant ovarian
follicles; however, little is known about the regulation of the IGF-2 gene or the interaction of …

Insulin‐like growth factor‐I (IGF‐I) stimulates the development of cultured rat pre‐antral follicles

J Zhao, MAM Taverne… - Molecular …, 2001 - Wiley Online Library
The aim of the present study is to investigate the effect of insulin‐like growth factor (IGF‐I) on
the development of cultured rat pre‐antral follicles. Pre‐antral follicles with a diameter …

[PDF][PDF] Insulin-like growth factor (IGF) system in the oocyte and somatic cells of bovine preantral follicles

DG Armstrong, G Baxter, CO Hogg, KJ Woad - REPRODUCTION …, 2002 - Citeseer
The insulin-like growth factor (IGF) system is an essential component of the intraovarian
mechanisms involved in the regulation of follicle growth and corpus luteum function …

The interplay of insulin-like growth factors, gonadotropins, and endocrine disruptors in ovarian follicular development and function

J Kwintkiewicz, LC Giudice - Seminars in reproductive medicine, 2009 - thieme-connect.com
Over the past 20 years, the expression, signaling mechanisms, and roles of members of the
insulin-like growth factor (IGF) family (ligands, receptors, binding proteins, and binding …

Insulin-like growth factor binding protein-2 and-4 messenger ribonucleic acid expression in bovine ovarian follicles: effect of gonadotropins and developmental status

DG Armstrong, G Baxter, CG Gutierrez, CO Hogg… - …, 1998 - academic.oup.com
This work is concerned with the role of insulin-like growth factor binding protein (IGFBP)-2
and-4 in the regulation of IGF bioactivity in bovine follicles during the development of …

Effects of IGF-I bioavailability on bovine preantral follicular development in vitro

FH Thomas, BK Campbell, DG Armstrong… - …, 2007 - rep.bioscientifica.com
The aim of this study was to determine the effect of regulation of IGF-I bioavailability on
preantral follicle development in vitro. Bovine preantral follicles were cultured for 6 days in …

The role of pituitary gonadotropins and intraovarian regulators in follicle development: A mini‐review

M Orisaka, Y Miyazaki, A Shirafuji… - Reproductive …, 2021 - Wiley Online Library
Background The process of follicle development is tightly regulated by pituitary
gonadotropins (follicle‐stimulating hormone [FSH] and luteinizing hormone [LH]) and …

The insulin‐like growth factor system: A key determinant role in the growth and selection of ovarian follicles? A comparative species study

S Mazerbourg, CA Bondy, J Zhou… - … in Domestic Animals, 2003 - Wiley Online Library
Contents The aim of the present paper is to make a comparative study of the expression of
the elements of the insulin‐like growth factor (IGF) system in different mammalian species …

[PDF][PDF] Expression of mRNA encoding IGF-I, IGF-II and type 1 IGF receptor in bovine ovarian follicles

DG Armstrong, CG Gutierrez, G Baxter… - Journal of …, 2000 - researchgate.net
IGFs regulate gonadotrophin-stimulated proliferation and differentiation of granulosa and
theca cells in vitro. However, the detailed pattern of mRNA expression of IGFs in bovine …