We have employed in situ hybridization histochemistry to map the cellular pattern of insulin-
like growth factor-I (IGF-I) and the IGF-I receptor gene expression in developing rat ovaries …

An inhibitor of FSH action on granulosa cells has been purified from porcine follicular fluid
using a combination of ammonium sulfate precipitation, dialysis in 30%(vol/vol) acetic acid …

Introduction I NSULIN-like growth factor-I (IGF-I) and its structural homologue, IGF-II, are low
molecular weight peptides that promote cellular mitosis and differentiation in a variety of …

Secreted by the anterior pituitary gland, growth hormone (GH) is a peptide that plays a
critical role in regulating cell growth, development, and metabolism in multiple targeted …

Levels of insulin-like growth factor-I (IGF-I), IGF-II, and IGF-binding proteins (IGFBPs) were
studied in ovine follicular fluid and serum with a view to determining their respective …

Ovarian reserve is determined by the number of primordial follicles in the ovary. Quiescent
primordial follicles are activated for growth and pass through stages of development before …

Although earlier studies focused on the hormonal regulation of antral and preovulatory
follicles, recent studies indicate the importance of the hormonal control mechanism for …

A growing body of evidence suggests that growth hormone (GH) plays a role in regulating
ovarian function by augmenting gonadotropin stimulation of granulosa cell differentiation …

Involvement of insulin-like growth factors (IGFs) and IGF binding proteins (IGFBPs) in
ovarian folliculogenesis has been extensively studied during the last decade. In all …

Context: FSH is routinely administered to in vitro fertilization patients to induce follicle
maturation. During this process, granulosa cells differentiate and acquire specific functional …