After the appearance of the first FDA‐approved antibody 25 years ago, antibodies have
become major therapeutic agents in the treatment of many human diseases, including …

Currently, antibodies play major role in treating a wide variety of human diseases (eg,
cancer, viral infection, inflammation). Those pharmaceutic antibodies have become major …

Various forms of recombinant monoclonal antibodies are being used increasingly, mainly for
therapeutic purposes. This review specifically focuses on what is now called antibody …

Since the development of antibody-production techniques, a number of immunoglobulins
have been developed on a large scale using conventional methods. Hybridoma technology …

Engineered antibodies currently represent over 30% of biopharmaceuticals in clinical trials
and their total worldwide sales continue to increase significantly. The importance of antibody …

▪ Abstract Antibodies are unique in their high affinity and specificity for a binding partner, a
quality that has made them one of the most useful molecules for biotechnology and …

It has been almost 100 years since von Behring and Kitasato received the first Nobel prize
for the discovery of passive immunotherapy and nearly 25 years since Köhler and Milstein …

The exquisite binding specificity of antibodies has made them valuable tools from the
laboratory to the clinic. Since the description of the murine hybridoma technology by Köhler …

As the field of antibody engineering continues its explosive growth, more and more scientists
around the world are striving to keep up with the latest developments. Now in its second …

The advent of modern antibody engineering has led to numerous successes in the
application of these proteins for cancer therapy in the 13 years since the first Food and Drug …