Estimated reductions in opioid overdose deaths with sustainment of public health interventions in 4 US States

J Chhatwal, PP Mueller, Q Chen, N Kulkarni… - JAMA network …, 2023 - jamanetwork.com
Importance In 2021, more than 80 000 US residents died from an opioid overdose. Public
health intervention initiatives, such as the Helping to End Addiction Long-term (HEALing) …

Projected estimates of opioid mortality after community-level interventions

BP Linas, A Savinkina, R Madushani, J Wang… - JAMA network …, 2021 - jamanetwork.com
Importance The United States is experiencing a crisis of opioid overdose. In response, the
US Department of Health and Human Services has defined a goal to reduce overdose …

Public Health Interventions and Overdose-Related Outcomes Among Persons With Opioid Use Disorder

N Nataraj, SM Rikard, K Zhang, X Jiang… - JAMA Network …, 2024 - jamanetwork.com
Importance Given the high number of opioid overdose deaths in the US and the complex
epidemiology of opioid use disorder (OUD), systems models can serve as a tool to identify …

Modeling mitigation strategies to reduce opioid-related morbidity and mortality in the US

J Ballreich, O Mansour, E Hu, F Chingcuanco… - JAMA network …, 2020 - jamanetwork.com
Importance The US opioid epidemic is complex and dynamic, yet relatively little is known
regarding its likely future impact and the potential mitigating impact of interventions to …

Interventions to address the opioid crisis—modeling predictions and consequences of inaction

ND Volkow, C Blanco - JAMA Network Open, 2021 - jamanetwork.com
The scale of the opioid crisis in the United States highlights the need to identify and
implement the most effective approaches to prevent overdose fatalities. Over the last 15 …

Simulating the simultaneous impact of medication for opioid use disorder and naloxone on opioid overdose death in eight New York counties

M Cerdá, AD Hamilton, A Hyder, C Rutherford… - …, 2024 - journals.lww.com
Background: The United States is in the midst of an opioid overdose epidemic; 28.3 per
100,000 people died of opioid overdose in 2020. Simulation models can help understand …

Reducing opioid use disorder and overdose deaths in the United States: a dynamic modeling analysis

EJ Stringfellow, TY Lim, K Humphreys… - Science …, 2022 - science.org
Opioid overdose deaths remain a major public health crisis. We used a system dynamics
simulation model of the US opioid-using population age 12 and older to explore the impacts …

Modeling health benefits and harms of public policy responses to the US opioid epidemic

AL Pitt, K Humphreys… - American journal of …, 2018 - ajph.aphapublications.org
Objectives. To estimate health outcomes of policies to mitigate the opioid epidemic.
Methods. We used dynamic compartmental modeling of US adults, in various pain, opioid …

Prevention of prescription opioid misuse and projected overdose deaths in the United States

Q Chen, MR Larochelle, DT Weaver, AP Lietz… - JAMA network …, 2019 - jamanetwork.com
Importance Deaths due to opioid overdose have tripled in the last decade. Efforts to curb this
trend have focused on restricting the prescription opioid supply; however, the near-term …

Effect of reductions in opioid prescribing on opioid use disorder and fatal overdose in the United States: a dynamic Markov model

GC Alexander, J Ballreich, O Mansour, DW Dowdy - Addiction, 2022 - Wiley Online Library
Background and aims Despite prescribing declines between 2011 and 2019, opioid
morbidity and mortality in the United States continued to rise during this period. We …