A direct action of human calcitonin gene-related peptide on isolated osteoclasts

M Zaidi, TJ Chambers, REG Das… - Journal of …, 1987 - joe.bioscientifica.com
The calcitonin gene encodes a small family of peptides: calcitonin, calcitonin gene-related
peptide (CGRP) and katacalcin. Whereas calcitonin is concerned with skeletal maintenance …

Effects of peptides from the calcitonin genes on bone and bone cells

M Zaidi, PJR Bevis, JL Beacham… - Quarterly Journal of …, 1988 - Wiley Online Library
The calcitonin‐calcitonin gene‐related peptide (CGRP) gene complex encodes a family of
novel peptides‐calcitonin, CGRP and katacalcin. Whereas calcitonin is a circulating …

Calcitonin gene-related peptide inhibits osteoclastic bone resorption: a comparative study

M Zaidi, K Fuller, PJR Bevis, RE GainesDas… - Calcified tissue …, 1987 - Springer
Besides the calcitonin (CT) precursor, the calcitonin gene also encodes another peptide—
calcitonin gene-related peptide (CGRP). We have previously reported that CGRP lowers …

Human Synthetic Calcitonin Gene-Related Peptide Inhibits Bone Resorption in Vitro

SM D'SOUZA, I MacIntyre, SI Girgis, GR Mundy - Endocrinology, 1986 - academic.oup.com
The calcitonin gene-related peptide (CGRP) is a pepticle which normally circulates. It is
encoded by the calcitonin gene, whose precise function is unknown. Since it has recently …

Human calcitonin gene-related peptide possesses weak inhibitory potency of bone resorptionin vitro

I Yamamoto, N Kitamura, J Aoki, C Shigeno… - Calcified tissue …, 1986 - Springer
Synthetic human calcitonin gene-related peptide (CGRP) was examined for the action on
the bone in vitro. Human CGRP inhibited bone resorption stimulated by both human …

Structure-activity relationship of human calcitonin-gene-related peptide

M Zaidi, SD Brain, JR Tippins, V Di Marzo… - Biochemical …, 1990 - portlandpress.com
The calcitonin-calcitonin-gene-related peptide (CGRP) gene complex encodes a small
family of peptides: calcitonin, CGRP and katacalcin. Calcitonin is a circulating hormone that …

Calcitonin and the peptides from the calcitonin gene

I MacIntyre, M Alevizaki, PJR Bevis… - … and Related Research®, 1987 - journals.lww.com
The α-calcitonin gene encodes a small family of peptides: Calcitonin, katacalcin, and
calcitonin generelated peptide (CGRP). Calcitonin and katacalcin are produced from one …

Structure‐activity relationships in calcitonin gene‐related peptide: Cyclic AMP response in a preosteoblast cell line (ks‐4)

D Thiebaud, T Akatsu, T Yamashita… - Journal of Bone and …, 1991 - Wiley Online Library
Synthetic analogs of chicken and human CGRP were used to define structure‐function
relationships in a murine osteoblast precursor cell line, KS‐4, that exhibits a substantial …

Further studies on the mode of action of calcitonin on isolated rat osteoclasts: pharmacological evidence for a second site mediating intracellular Ca2+ mobilization …

A Alam, CMR Bax, VS Shankar, BE Bax… - Journal of …, 1993 - joe.bioscientifica.com
Calcitonin is a circulating polypeptide that inhibits bone resorption by inducing both
quiescence (Q effect) and retraction (R effect) in osteoclasts. Two structurally related …

[引用][C] Calcitonin, osteoclasts, and bone turnover

S Wallach, JB Carstens, LV Avioli - Calcified tissue international, 1990 - Springer
Since the discovery of calcitonin in the early 1960s, considerable controversy has
developed regarding the cell-specific responsivity to this peptide, species differences in …