We prospectively investigated pathological modifications in the corticospinal tract (CST), by
diffusion tensor imaging (DTI) in 14 patients with sporadic amyotrophic lateral sclerosis …

Purpose Diffusion tensor imaging can evaluate the cerebral white matter quantitatively using
fractional anisotropy (FA) and also can extract a certain tract by tractography, but these two …

Amyotrophic lateral sclerosis (ALS) is a severe neurodegenerative disease, which primarily
targets the motor system. The structural integrity of the motor network and the way it is …

Diffusion tensor imaging (DTI) allows the in vivo imaging of pathological white matter
alterations, either with unbiased voxel-wise or hypothesis-guided tract-based analysis …

Objective To evaluate MRI-based parameters as biomarkers of Amyotrophic Lateral
Sclerosis (ALS) progression. Methods Twenty-seven patients and 27 controls performed two …

Studies involving diffusion tensor imaging (DTI) of amyotrophic lateral sclerosis (ALS) with
whole-brain voxel-based analysis yielded variable findings. A systematic review was …

The aim of this work was to investigate white-matter microstructural changes within and
outside the corticospinal tract in classical amyotrophic lateral sclerosis (ALS) and in lower …

Objective To construct a clinical diagnostic biomarker using state-of-the-art microstructural
MRI in the motor cortex of people with amyotrophic lateral sclerosis (ALS). Methods Clinical …

Purpose To determine if decline in corpus callosum (CC) white matter integrity in patients
with amyotrophic lateral sclerosis (ALS) is localized to motor‐related areas. Materials and …

Background and purpose Magnetic resonance diffusivity indices have been repeatedly
proposed as biomarkers of neurodegeneration in amyotrophic lateral sclerosis (ALS), but no …