Shared and drug-specific effects of atomoxetine and methylphenidate on inhibitory brain dysfunction in medication-naive ADHD boys

A Cubillo, AB Smith, N Barrett, V Giampietro… - Cerebral …, 2014 - academic.oup.com
The stimulant methylphenidate (MPX) and the nonstimulant atomoxetine (ATX) are the most
commonly prescribed medications for attention deficit hyperactivity disorder (ADHD) …

Differential therapeutic effects of 12-week treatment of atomoxetine and methylphenidate on drug-naive children with attention deficit/hyperactivity disorder: A counting …

TL Chou, S Chia, CY Shang, SSF Gau - European …, 2015 - Elsevier
Methylphenidate and atomoxetine are effective in treating attention-deficit/hyperactivity
disorder (ADHD) with underlying distinct pharmacological mechanisms. To relate neural …

Drug-specific laterality effects on frontal lobe activation of atomoxetine and methylphenidate in attention deficit hyperactivity disorder boys during working memory

A Cubillo, AB Smith, N Barrett, V Giampietro… - Psychological …, 2014 - cambridge.org
BackgroundThe catecholamine reuptake inhibitors methylphenidate (MPH) and atomoxetine
(ATX) are the most common treatments for attention deficit hyperactivity disorder (ADHD) …

Common and unique therapeutic mechanisms of stimulant and nonstimulant treatments for attention-deficit/hyperactivity disorder

KP Schulz, J Fan, ACV Bédard… - Archives of general …, 2012 - jamanetwork.com
Context Attention-deficit/hyperactivity disorder (ADHD) is a highly prevalent and impairing
psychiatric disorder that affects both children and adults. There are Food and Drug …

Differential effects of methylphenidate and atomoxetine on intrinsic brain activity in children with attention deficit hyperactivity disorder

CY Shang, CG Yan, HY Lin, WY Tseng… - Psychological …, 2016 - cambridge.org
BackgroundMethylphenidate and atomoxetine are commonly prescribed for treating
attention deficit hyperactivity disorder (ADHD). However, their therapeutic neural …

Methylphenidate and atomoxetine normalise fronto-parietal underactivation during sustained attention in ADHD adolescents

OS Kowalczyk, AI Cubillo, A Smith, N Barrett… - European …, 2019 - Elsevier
Problems with sustained attention are a key clinical feature of Attention Deficit/Hyperactivity
Disorder (ADHD) which also manifests in poor performance and abnormal fronto-striato …

Striatal activation predicts differential therapeutic responses to methylphenidate and atomoxetine

KP Schulz, ACV Bédard, J Fan, TB Hildebrandt… - Journal of the American …, 2017 - Elsevier
Objective Methylphenidate has prominent effects in the dopamine-rich striatum that are
absent for the selective norepinephrine transporter inhibitor atomoxetine. This study tested …

Methylphenidate normalizes fronto-striatal underactivation during interference inhibition in medication-naive boys with attention-deficit hyperactivity disorder

K Rubia, R Halari, A Cubillo, AB Smith… - …, 2011 - nature.com
Youth with attention deficit hyperactivity disorder (ADHD) have deficits in interference
inhibition, which can be improved with the indirect catecholamine agonist methylphenidate …

Comparison of the inhibitory and excitatory effects of ADHD medications methylphenidate and atomoxetine on motor cortex

DL Gilbert, KR Ridel, FR Sallee, J Zhang… - …, 2006 - nature.com
Stimulant and norepinephrine (NE) reuptake inhibitor medications have different effects at
the neuronal level, but both reduce symptoms of attention deficit hyperactivity disorder …

Atomoxetine increases fronto-parietal functional MRI activation in attention-deficit/hyperactivity disorder: a pilot study

G Bush, J Holmes, LM Shin, C Surman, N Makris… - Psychiatry Research …, 2013 - Elsevier
We hypothesized that atomoxetine (ATMX) would produce similar brain effects in attention-
deficit/hyperactivity disorder (ADHD) as those of methylphenidate (MPH). Eleven ADHD …