Acute intermittent hypoxia boosts spinal plasticity in humans with tetraplegia

L Christiansen, B Chen, Y Lei, MA Urbin… - Experimental …, 2021 - Elsevier
Paired corticospinal-motoneuronal stimulation (PCMS) elicits spinal synaptic plasticity in
humans with chronic incomplete cervical spinal cord injury (SCI). Here, we examined …

Spinal cord stimulation and rehabilitation in an individual with chronic complete L1 paraplegia due to a conus medullaris injury: motor and functional outcomes at 18 …

MO Krucoff, R Gramer, D Lott, E Kale… - Spinal Cord Series and …, 2020 - nature.com
Introduction Epidural electrical stimulation of the conus medullaris has helped facilitate
native motor recovery in individuals with complete cervicothoracic spinal cord injuries (SCI) …

Acute Strength Training Increases Responses to Stimulation of Corticospinal Axons.

JL Nuzzo, BK Barry, SC Gandevia… - Medicine and science in …, 2016 - europepmc.org
Purpose Acute strength training of forearm muscles increases resting twitch forces from
motor cortex stimulation. It is unclear if such effects are spinal in origin and if they also occur …

Targeted transcutaneous cervical spinal cord stimulation promotes lasting upper limb recovery in spinal cord and peripheral nerve injury

S Chandrasekaran, N Bhagat, R Ramdeo… - … Clinical Research in …, 2023 - brainstimjrnl.com
Long-term recovery of limb function is a significant unmet need in people with paralysis.
Targeted neuromodulation through epidural stimulation of the spinal cord, when paired with …

[HTML][HTML] The effect of electrical stimulation on corticospinal excitability is dependent on application duration: a same subject pre-post test design

RK Andrews, SM Schabrun, MC Ridding… - Journal of …, 2013 - Springer
Background In humans, corticospinal excitability is known to increase following motor
electrical stimulation (ES) designed to mimic a voluntary contraction. However, whether the …

Electrical stimulation of the cervical dorsal roots enables functional arm and hand movements in monkeys with cervical spinal cord injury

B Barra, S Conti, MG Perich, K Zhuang, G Schiavone… - Biorxiv, 2020 - biorxiv.org
Regaining arm motor control is a high priority for people with cervical spinal cord injury.
Unfortunately, no therapy can reverse upper limb paralysis. Promising neurotechnologies …

[HTML][HTML] Increased voluntary activation of the elbow flexors following a single session of spinal manipulation in a subclinical neck pain population

M Kingett, K Holt, IK Niazi, RW Nedergaard, M Lee… - Brain Sciences, 2019 - mdpi.com
To investigate the effects of a single session of spinal manipulation (SM) on voluntary
activation of the elbow flexors in participants with subclinical neck pain using an interpolated …

Reciprocal EMG control of elbow extension by FES

JP Giuffrida, PE Crago - IEEE Transactions on Neural Systems …, 2001 - ieeexplore.ieee.org
Elbow extension is critical in performing activities of daily living. Individuals with a C5-C6
spinal cord injury have paralyzed elbow extensors, yet retain weak to strong voluntary …

Electrical neuromodulation of the cervical spinal cord facilitates forelimb skilled function recovery in spinal cord injured rats

M Alam, G Garcia-Alias, B Jin, J Keyes, H Zhong… - Experimental …, 2017 - Elsevier
Enabling motor control by epidural electrical stimulation of the spinal cord is a promising
therapeutic technique for the recovery of motor function after a spinal cord injury (SCI) …

High-intensity, low-frequency repetitive transcranial magnetic stimulation enhances excitability of the human corticospinal pathway

JM D'Amico, SC Dongés… - Journal of …, 2020 - journals.physiology.org
Paired corticospinal-motoneuronal stimulation (PCMS) is the repeated pairing of
transcranial magnetic stimulation (TMS) with peripheral nerve stimulation to modify …