Human dendritic cell subsets for vaccination
P Dubsky, H Ueno, B Piqueras, J Connolly… - Journal of clinical …, 2005 - Springer
TProtective immunity results from the interplay of antigen (Ag)-nonspecific innate immunity
and Ag-specific adaptive immunity. The cells and molecules of the innate system employ …
and Ag-specific adaptive immunity. The cells and molecules of the innate system employ …
Human dendritic cells (DCs) are derived from distinct circulating precursors that are precommitted to become CD1c+ or CD141+ DCs
In humans, conventional dendritic cells (cDCs) exist as two unique populations
characterized by expression of CD1c and CD141. cDCs arise from increasingly restricted …
characterized by expression of CD1c and CD141. cDCs arise from increasingly restricted …
The XC chemokine receptor 1 is a conserved selective marker of mammalian cells homologous to mouse CD8α+ dendritic cells
K Crozat, R Guiton, V Contreras, V Feuillet… - Journal of Experimental …, 2010 - rupress.org
Human BDCA3+ dendritic cells (DCs) were suggested to be homologous to mouse CD8α+
DCs. We demonstrate that human BDCA3+ DCs are more efficient than their BDCA1+ …
DCs. We demonstrate that human BDCA3+ DCs are more efficient than their BDCA1+ …
CD141+ dendritic cells produce prominent amounts of IFN-α after dsRNA recognition and can be targeted via DEC-205 in humanized mice
Functional differences between human dendritic cell (DC) subsets and the potential benefits
of targeting them with vaccines remain poorly defined. Here we describe that mice with …
of targeting them with vaccines remain poorly defined. Here we describe that mice with …
Phenotypic and functional characterization of mouse hepatic CD8α+ lymphoid-related dendritic cells
PJ O'Connell, AE Morelli, AJ Logar… - The Journal of …, 2000 - journals.aai.org
Recently, attention has focussed on phenotypic and functional differences between classic
myeloid dendritic cells (DC), and DC that reportedly develop from an early, committed …
myeloid dendritic cells (DC), and DC that reportedly develop from an early, committed …
Monocyte‐derived dendritic cells in innate and adaptive immunity
B León, C Ardavín - Immunology and cell biology, 2008 - Wiley Online Library
Monocytes have been classically considered essential elements in relation with innate
immune responses against pathogens, and inflammatory processes caused by external …
immune responses against pathogens, and inflammatory processes caused by external …
Complexity of dendritic cell subsets and their function in the host immune system
Dendritic cells (DCs) are professional antigen‐presenting cells that are critical for induction
of adaptive immunity and tolerance. Traditionally DCs have been divided into two discrete …
of adaptive immunity and tolerance. Traditionally DCs have been divided into two discrete …
Functional specialization of human circulating CD16 and CD1c myeloid dendritic-cell subsets
D Piccioli, S Tavarini, E Borgogni, V Steri… - Blood, The Journal …, 2007 - ashpublications.org
Human blood contains 2 populations of dendritic cells (DCs): plasmacytoid and myeloid
(mDC). mDCs are subdivided into 3 subsets using the surface markers CD16, CD1c, and …
(mDC). mDCs are subdivided into 3 subsets using the surface markers CD16, CD1c, and …
Chemotactic response toward chemokines and its regulation by transforming growth factor-β1 of murine bone marrow hematopoietic progenitor cell-derived different …
Dendritic cells (DCs) are highly specialized antigen-presenting cells that distribute widely in
all organs. DCs initiate the primary immune response and activate naive T cells and B cells …
all organs. DCs initiate the primary immune response and activate naive T cells and B cells …