Tumor metabolism‐engineered composite nanoplatforms potentiate sonodynamic therapy via reshaping tumor microenvironment and facilitating electron–hole pairs' …

X Guan, HH Yin, XH Xu, G Xu, Y Zhang… - Advanced Functional …, 2020 - Wiley Online Library
Reactive oxygen species (ROS) depletion and low ROS production that result from the
intratumoral redox metabolism equilibrium and low energy conversion efficiency from …

Nanomaterials-based tumor microenvironment modulation for magnifying sonodynamic therapy

L Song, L Lu, Y Pu, H Yin, K Zhang - Accounts of Materials …, 2022 - ACS Publications
Conspectus Sonodynamic therapy (SDT) is a noninvasive and more preferable therapeutic
modality than photodynamic therapy (PDT) due to deeper tissue penetration, which utilizes …

[HTML][HTML] Engineered gold/black phosphorus nanoplatforms with remodeling tumor microenvironment for sonoactivated catalytic tumor theranostics

T Chen, W Zeng, C Tie, M Yu, H Hao, Y Deng, Q Li… - Bioactive Materials, 2022 - Elsevier
The imbalance between oxidants and antioxidants in cancer cells would evoke oxidative
stress-induced cell death, which has been demonstrated to be highly effective in treating …

Two-Dimensional MXene-Originated In Situ Nanosonosensitizer Generation for Augmented and Synergistic Sonodynamic Tumor Nanotherapy

M Zhang, D Yang, C Dong, H Huang, G Feng, Q Chen… - ACS …, 2022 - ACS Publications
Despite the merits of high tissue-penetrating depth, no ionizing radiation, and low cost,
sonodynamic therapy (SDT) still suffers from a low quantum yield of reactive oxygen species …

Metal–Organic Framework (MOF)‐Based Ultrasound‐Responsive Dual‐Sonosensitizer Nanoplatform for Hypoxic Cancer Therapy

C Zhang, L Xin, J Li, J Cao, Y Sun… - Advanced …, 2022 - Wiley Online Library
Sonodynamic therapy (SDT), which uses reactive oxygen species to target tumors, has
shown promise in the management of unresectable cancers. However, the hypoxic tumor …

Ultrasound‐activated oxygen and ROS generation nanosystem systematically modulates tumor microenvironment and sensitizes sonodynamic therapy for hypoxic …

J Fu, T Li, Y Zhu, Y Hao - Advanced Functional Materials, 2019 - Wiley Online Library
Sonodynamic therapy (SDT) is noninvasive and possesses high body‐penetration depth,
showing great potential for the treatment of deep‐seated solid tumors. The efficacy of SDT …

In-situ TiO2-x decoration of titanium carbide MXene for photo/sono-responsive antitumor theranostics

DY Zhang, H Liu, MR Younis, S Lei, Y Chen… - Journal of …, 2022 - Springer
Background Sonodynamic therapy (SDT) has emerged as a noninvasive therapeutic
modality that involves sonosensitizers and low-intensity ultrasound. However, owing to the …

Recent advances in nanomaterial-based augmented sonodynamic therapy of cancer

W Um, PK EK, J Lee, CH Kim, DG You… - Chemical …, 2021 - pubs.rsc.org
With interest in non-invasiveness and safety in cancer treatment, sonodynamic therapy
(SDT) has emerged as a promising alternative to conventional cancer therapies. SDT offers …

A MXene-derived redox homeostasis regulator perturbs the Nrf2 antioxidant program for reinforced sonodynamic therapy

H Wang, X Liu, X Yan, J Fan, D Li, J Ren, X Qu - Chemical Science, 2022 - pubs.rsc.org
Ultrasound (US)-mediated sonodynamic therapy (SDT) has emerged as a spatiotemporally
controllable therapeutic modality in combating cancer because of its high tissue-penetration …

Metal-phenolic network-enabled lactic acid consumption reverses immunosuppressive tumor microenvironment for sonodynamic therapy

Z Zhang, B Li, L Xie, W Sang, H Tian, J Li, G Wang… - ACS …, 2021 - ACS Publications
Nanomedicine has revolutionized cancer therapeutic strategies but has not completely
changed the outcomes of tricky tumors that evolve a sophisticated immunosuppressive …