Curvature and Lipid Packing Modulate the Elastic Properties of Lipid Assemblies: Comparing HII and Lamellar Phases

N Johner, D Harries, G Khelashvili - The journal of physical …, 2014 - ACS Publications
Accumulating evidence indicates that membrane reshaping and fusion processes, as well
as regulation of membrane protein function, depend on lipid composition. Although it is …

Implementation of a methodology for determining elastic properties of lipid assemblies from molecular dynamics simulations

N Johner, D Harries, G Khelashvili - BMC bioinformatics, 2016 - Springer
Background The importance of the material properties of membranes for diverse cellular
processes is well established. Notably, the elastic properties of the membrane, which …

Origin of the nonlinear structural and mechanical properties in oppositely curved lipid mixtures

S Gupta, J Soni, A Kumar, T Mandal - The Journal of Chemical Physics, 2023 - pubs.aip.org
Structural and mechanical properties of membranes such as thickness, tail order, bending
modulus and curvature energetics play crucial role in controlling various cellular functions …

[HTML][HTML] Cooperative elastic stresses, the hydrophobic effect, and lipid tilt in membrane remodeling

VA Frolov, J Zimmerberg - FEBS letters, 2010 - Elsevier
One of the fundamental properties of biological membranes is the high lateral integrity
provided by the lipid bilayer, the structural core and the foundation of their barrier function …

Molecular mechanisms of spontaneous curvature and softening in complex lipid bilayer mixtures

HJ Lessen, KC Sapp, AH Beaven, R Ashkar, AJ Sodt - Biophysical Journal, 2022 - cell.com
Membrane reshaping is an essential biological process. The chemical composition of lipid
membranes determines their mechanical properties and thus the energetics of their shape …

Spatial extent of a single lipid's influence on bilayer mechanics

KC Sapp, AH Beaven, AJ Sodt - Physical Review E, 2021 - APS
To what spatial extent does a single lipid affect the mechanical properties of the membrane
that surrounds it? The lipid composition of a membrane determines its mechanical …

[HTML][HTML] Determining the pivotal plane of fluid lipid membranes in simulations

X Wang, M Deserno - The Journal of chemical physics, 2015 - pubs.aip.org
Each leaflet of a curved lipid membrane contains a surface at which the area strain
vanishes, the so-called pivotal plane. Its distance z 0 from the bilayer's midplane arises in …

Lipid membranes: From self-assembly to elasticity

MM Terzi, M Deserno - The Role of Mechanics in the Study of Lipid …, 2018 - Springer
In aqueous solution, lipid molecules spontaneously assemble into macroscopic bilayer
membranes, which have highly interesting mechanical properties. In this chapter, we first …

Spontaneous curvature, differential stress, and bending modulus of asymmetric lipid membranes

A Hossein, M Deserno - Biophysical Journal, 2020 - cell.com
Lipid bilayers can exhibit asymmetric states, in which the physical characteristics of one
leaflet differ from those of the other. This most visibly manifests in a different lipid …

Softening in two-component lipid mixtures by spontaneous curvature variance

A Hossein, AH Beaven, K Sapp… - The Journal of Physical …, 2024 - ACS Publications
The bending modulus of a lipid bilayer quantifies its mechanical resistance to curvature. It is
typically understood in terms of thickness; eg, thicker bilayers are usually stiffer. Here, we …