Monocytes and macrophages are important components of the immune system, specialized
in either removing pathogens as part of innate immunity or contributing to adaptive immunity …

Diversity and plasticity are the hallmarks of cells from the monocyte–macrophage lineage.
Macrophages undergo classical M1 or alternative M2 activation in response to the …

Abstract microRNAs (miRNAs) play a crucial role in tissue development and the pathology of
various diseases. However, the effects and roles of miRNAs in macrophage polarization …

microRNAs (miRNAs) are small noncoding RNAs that regulate gene expression at a
posttranscriptional level and play a crucial role in the development of cells of the immune …

Polarization of macrophages is regulated through complex signaling networks. Correlating
miRNA and mRNA expression over time after macrophage polarization has not yet been …

Macrophages respond to external stimuli with rapid changes in expression of many genes.
Different combinations of external stimuli lead to distinct polarized activation patterns …

Macrophage polarization is a process through which macrophages attain unique functional
features as a response to certain stimuli from their niche. Lipopolysaccharide and Th1 …

Neuroinflammation contributes to many neurologic disorders including Alzheimer's disease,
multiple sclerosis, and stroke. Microglia is brain resident myeloid cells and have emerged as …

The ability of a healthy immune system to clear the plethora of antigens it encounters
incessantly relies on the enormous plasticity displayed by the comprising cell types …

Diversity and plasticity are hallmarks of macrophages. Classically activated macrophages
are considered to promote T helper type 1 responses and have strong microbicidal, pro …