Engineering defected 2D Pd/H-TiO2 nanosonosensitizers for hypoxia alleviation and enhanced sono-chemodynamic cancer nanotherapy

X Qiao, L Xue, H Huang, X Dai, Y Chen… - Journal of …, 2022 - Springer
Background Sonodynamic therapy (SDT) is a burgeoning modality for cancer therapy owing
to its high tissue-penetrating capability, controllability and safety. Whereas, the undesirable …

Two-dimensional graphene augments nanosonosensitized sonocatalytic tumor eradication

C Dai, S Zhang, Z Liu, R Wu, Y Chen - ACS nano, 2017 - ACS Publications
Ultrasound (US) can activate sonosensitizers for sonodynamic therapy (SDT), but the low
activation efficiency and therapeutic outcome significantly hinder its further clinical …

Nanosonosensitization by using copper–cysteamine nanoparticles augmented sonodynamic cancer treatment

P Wang, X Wang, L Ma, S Sahi, L Li… - Particle & Particle …, 2018 - Wiley Online Library
Sonodynamic therapy (SDT), as a newly emerging and promising modality for cancer
treatment, has been extensively investigated but with limited therapeutic outcome because …

Metalloporphyrin complex‐based nanosonosensitizers for deep‐tissue tumor theranostics by noninvasive sonodynamic therapy

A Ma, H Chen, Y Cui, Z Luo, R Liang, Z Wu, Z Chen… - Small, 2019 - Wiley Online Library
Metal complexes are widely used as anticancer drugs, while the severe side effects of
traditional chemotherapy require new therapeutic modalities. Sonodynamic therapy (SDT) …

Nanomaterials-based tumor microenvironment modulation for magnifying sonodynamic therapy

L Song, L Lu, Y Pu, H Yin, K Zhang - Accounts of Materials …, 2022 - ACS Publications
Conspectus Sonodynamic therapy (SDT) is a noninvasive and more preferable therapeutic
modality than photodynamic therapy (PDT) due to deeper tissue penetration, which utilizes …

Platelet membrane-coated C-TiO2 hollow nanospheres for combined sonodynamic and alkyl-radical cancer therapy

W Guo, T Wang, C Huang, S Ning, Q Guo, W Zhang… - Nano Research, 2023 - Springer
The therapeutic efficiency of sonodynamic therapy (SDT) mainly depends on the presence
of oxygen (O2) to generate harmful reactive oxygen species (ROS); thus, the hypoxic tumor …

Engineering molybdenum‐assisted tellurium nanosonosensitizers for enhanced sonodynamic tumor nanotherapy

L Dong, W Li, Y Luo, C Liu, K Li… - Advanced Functional …, 2023 - Wiley Online Library
Materdicine‐augmented sonodynamic therapy has emerged as an efficient noninvasive
strategy for cancer treatment by generating reactive oxygen species associated with the …

Micro/nanoparticle‐augmented sonodynamic therapy (SDT): breaking the depth shallow of photoactivation

X Qian, Y Zheng, Y Chen - Advanced materials, 2016 - Wiley Online Library
The fast development of photoactivation for cancer treatment provides an efficient photo‐
therapeutic strategy for cancer treatment, but traditional photodynamic or photothermal …

Reactive oxygen species-manipulated drug release from a smart envelope-type mesoporous titanium nanovehicle for tumor sonodynamic-chemotherapy

J Shi, Z Chen, B Wang, L Wang, T Lu… - ACS applied materials …, 2015 - ACS Publications
Despite advances in drug delivery systems (DDSs), the stimuli-responsive controlled
release DDSs with high spatial/temporal resolution are still the best choice. Herein, a novel …

MOF‐derived double‐layer hollow nanoparticles with oxygen generation ability for multimodal imaging‐guided sonodynamic therapy

X Pan, W Wang, Z Huang, S Liu, J Guo… - Angewandte …, 2020 - Wiley Online Library
The high reactive oxygen species (ROS) generation ability and simple construction of
sonosensitizer systems remain challenging in sonodynamic therapy against the hypoxic …