Calcitonin was discovered as a hypocalcemic principal that was initially thought to originate
from the parathyroid gland. This view was corrected subsequently, and an origin from the …

Calcitonin is a thirty-two amino acid peptide that contains an N-terminal disulphide bridge
and a C-terminal prolineamide residue. It is released from thyroid parafollicular C-cells and …

Calcitonin (CT) was first reported as a hypocalcemic principle, initially thought to originate
from the parathyroid gland, a view subsequently corrected to an origin from parafollicular C …

Calcitonin, a potent hypocalcemic hormone produced by the C‐cells of the thyroid, was first
discovered by Harold Copp in 1962. The physiological significance of calcitonin has been …

Calcitonin was discovered over 50 yr ago as a new hormone that rapidly lowers circulating
calcium levels. This effect is caused by the inhibition of calcium efflux from bone, as …

Calcitonin was originally discovered as a hypocalcemic factor synthesized by thyroid
parafollicular C cells. Early experiments demonstrated that calcitonin inhibited bone …

The 'calcitonin family'is a group of peptide hormones that share structural similarities with
calcitonin, and includes calcitonin gene-related peptide (CGRP), amylin, adrenomedullin …

The peptide calcitonin (CT) was initially discovered in 1962 as a novel hypocalcemic
hormone. This hypocalcemic response was principally due to a potent inhibitory action of CT …

In this issue of the JCI, the elegant publication by Hoff and colleagues (1), by serendipity or
on purpose, falls on the 40th anniversary of the discovery of calcitonin (CT) as a …

Osteoporosis is the most prevalent metabolic bone disease and is characterized by
diminished bone strength predisposing to an increased risk of fracture. Its incidence is …